2020 Publications

The following list highlights BRI's 2020 publications. More selective listings of publications are also included on scientist biography pages. BRI Principal Investigators are listed in bold.

Abdelsamed HA, Zebley CC, Nguyen H, Rutishauser RL, Fan Y, Ghoneim HE, Crawford JC, Alfei F, Alli S, Ribeiro SP, Castellaw AH, McGargill MA, Jin H, Boi SK, Speake C, Serti E, Turka LA, Busch ME, Stone M, Deeks SG, Sekaly RP, Zehn D, James EA, Nepom GT, Youngblood B. Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes. Nat Immunol. 2020 Mar 30. doi: 10.1038/s41590-020-0633-5. PMID: 32231298 | PMC7183435

Acharya M, Raso F, Sagadiev S, Gilbertson E, Kadavy L, Li QZ, Yan M, Stuart LM, Hamerman JA, Lacy-Hulbert A. B Cell αv Integrins Regulate TLR-Driven Autoimmunity. J Immunol. 2020 Oct 1;205(7):1810-1818. doi: 10.4049/jimmunol.1901056. Epub 2020 Aug 28. PMID: 32859730 | PMC7504890

Alonge KM, Mirzadeh Z, Scarlett JM, Logsdon AF, Brown JM, Cabrales E, Chan CK, Kaiyala KJ, Bentsen MA, Banks WA, Guttman M, Wight TN, Morton GJ, Schwartz MW. Hypothalamic perineuronal net assembly is required for sustained diabetes remission induced by fibroblast growth factor 1 in rats. Nat Metab. 2020 Oct;2(10):1025-1033. doi: 10.1038/s42255-020-00275-6. Epub 2020 Sep 7. PMID: 32895577 | PMC7572652

Arribas-Layton D, Guyer P, Delong T, Dang M, Chow IT, Speake C, Greenbaum CJ, Kwok WW, Baker RL, Haskins K, James EA. Hybrid Insulin Peptides are Recognized by Human T Cells in the Context of DRB1*04:01. Diabetes. 2020 Apr 14. pii: db190620. doi: 10.2337/db19-0620. PMID: 32291282 | PMC7306133

Baharom F, Ramirez-Valdez RA, Tobin KKS, Yamane H, Dutertre CA, Khalilnezhad A, Reynoso GV, Coble VL, Lynn GM, Mulè MP, Martins AJ, Finnigan JP, Zhang XM, Hamerman JA, Bhardwaj N, Tsang JS, Hickman HD, Ginhoux F, Ishizuka AS, Seder RA. Intravenous nanoparticle vaccination generates stem-like TCF1+ neoantigen-specific CD8+ T cells. Nat Immunol. 2020 Nov 2. doi: 10.1038/s41590-020-00810-3. PMID: 33139915 | PMC7746638

Barone SM, Paul AGA, Muehling LM, Lannigan JA, Kwok WW, Turner RB, Woodfolk JA, Irish JM. Unsupervised machine learning reveals key immune cell subsets in COVID-19, rhinovirus infection, and cancer therapy. bioRxiv. 2020 Aug 1:2020.07.31.190454. doi: 10.1101/2020.07.31.190454. PMID: 32766581 | PMC7402038

Barretto KT, Brockman-Schneider RA, Kuipers I, Basnet S, Bochkov YA, Altman MC, Jarjour NN, Gern JE, Esnault S. Human Airway Epithelial Cells Express a Functional IL-5 Receptor. Allergy 2020 Apr 4. doi: 10.1111/all.14297. PMID: 32246831 | PMC7387204

Battaglia M, Buckner JH, Levings MK, Richardson SJ, Wong FS, Tree TI. Identifying the 'Achilles Heel' of type 1 diabetes. Clin Exp Immunol. 2020 Dec 24. doi: 10.1111/cei.13570. PMID: 33368173 | PMC8062995

Bemis EA, Demoruelle MK, Seifert JA, Polinski KJ, Weisman MH, Buckner JH, Gregersen PK, Mikuls TR, ODell JR, Keating RM, Deane KD, Holers VM, Norris JM. Factors associated with progression to inflammatory arthritis in first-degree relatives of individuals with RA following autoantibody positive screening in a non-clinical setting. Ann Rheum Dis. 2020 Sep 14:annrheumdis-2020-217066. doi: 10.1136/annrheumdis-2020-217066. PMID: 32928740 | PMC7855648

Berkson JD, Slichter CK, DeBerg HA, Delaney MA, Woodward-Davis AS, Maurice NJ, Lwo Y, Ko A, Hsu J, Chiu YW, Linsley PS, Dixon D, Prlic M. Inflammatory Cytokines Induce Sustained CTLA-4 Cell Surface Expression on Human MAIT Cells. Immunohorizons. 2020 Jan 23;4(1):14-22. doi: 10.4049/immunohorizons.1900061. PMID: 31974109 | PMC7357853

Bettelli E, Campbell DJ. Circulating TFH cells as a marker for early therapeutic intervention in T1D. Nat Immunol. 2020 Oct;21(10):1141-1142. doi: 10.1038/s41590-020-0766-6. PMID: 32873972

Bissonnette EY, Lauzon-Joset JF, Debley JS, Ziegler SF. Cross-Talk Between Alveolar Macrophages and Lung Epithelial Cells is Essential to Maintain Lung Homeostasis. Front Immunol. 2020 Oct 15;11:583042. doi: 10.3389/fimmu.2020.583042. PMID: 33178214 | PMC7593577

Biswas A, Roy IM, Babu PC, Manesia J, Schouteden S, Vijayakurup V, Anto RJ, Huelsken J, Lacy-Hulbert A, Verfaillie CM, Khurana S. The Periostin/Integrin-αv Axis Regulates the Size of Hematopoietic Stem Cell Pool in the Fetal Liver. Stem Cell Reports. 2020 Aug 11;15(2):340-357. doi: 10.1016/j.stemcr.2020.06.022. Epub 2020 Jul 30. PMID: 32735820 | PMC7419718

Bogdani M, Speake C, Dufort MJ, Johnson PY, Larmore MJ, Day AJ, Wight TN, Lernmark Å, Greenbaum CJ. Hyaluronan deposition in islets may precede and direct the location of islet immune-cell infiltrates. Diabetologia. 2020 Jan 6. doi: 10.1007/s00125-019-05066-7. PMID: 31907557 | PMC7002022

Bogun MM, Bundy BN, Goland RS, Greenbaum CJ. C-Peptide Levels in Subjects Followed Longitudinally Before and After Type 1 Diabetes Diagnosis in TrialNet. Diabetes Care. 2020 May 26;dc192288. doi: 10.2337/dc19-2288. PMID: 32457058 | PMC7372058

Bolouri H, Young M, Beilke J, Johnson R, Fox B, Huang L, Santini CC, Hill CM, Vries AVV, Shannon PT, Dervan A, Sivakumar P, Trotter M, Bassett D, Ratushny A. Integrative network modeling reveals mechanisms underlying T cell exhaustion. Sci Rep. 2020 Feb 5;10(1):1915. doi: 10.1038/s41598-020-58600-8. PMID: 32024856 | PMC7002445

Boyd DF, Allen EK, Randolph AG, Guo XJ, Weng Y, Sanders CJ, Bajracharya R, Lee NK, Guy CS, Vogel P, Guan W, Li Y, Liu X, Novak T, Newhams MM, Fabrizio TP, Wohlgemuth N, Mourani PM; PALISI Pediatric Intensive Care Influenza (PICFLU) Investigators, Wight TN, Schultz-Cherry S, Cormier SA, Shaw-Saliba K, Pekosz A, Rothman RE, Chen KF, Yang Z, Webby RJ, Zhong N, Crawford JC, Thomas PG. Exuberant fibroblast activity compromises lung function via ADAMTS4. Nature. 2020 Nov;587(7834):466-471. doi: 10.1038/s41586-020-2877-5. Epub 2020 Oct 28. Erratum in: Nature. 2020 Nov 18; PMID: 33116313 | PMC7883627

Boyd DF, Allen EK, Randolph AG, Guo XJ, Weng Y, Sanders CJ, Bajracharya R, Lee NK, Guy CS, Vogel P, Guan W, Li Y, Liu X, Novak T, Newhams MM, Fabrizio TP, Wohlgemuth N, Mourani PM; PALISI Pediatric Intensive Care Influenza (PICFLU) Investigators, Wight TN, Schultz-Cherry S, Cormier SA, Shaw-Saliba K, Pekosz A, Rothman RE, Chen KF, Yang Z, Webby RJ, Zhong N, Crawford JC, Thomas PG. Publisher Correction: Exuberant fibroblast activity compromises lung function via ADAMTS4. Nature. 2020 Dec;588(7836):E5. doi: 10.1038/s41586-020-2987-0. Erratum for: Nature. 2020 Nov;587(7834):466-471. PMID: 33208953

Brilland B, Scherlinger M, Khoryati L, Goret J, Duffau P, Lazaro E, Charrier M, Guillotin V, Richez C, Blanco P. Platelets and IgE: Shaping the Innate Immune Response in Systemic Lupus Erythematosus. Clin Rev Allergy Immunol. 2020 Apr;58(2):194-212. doi: 10.1007/s12016-019-08744-x. PMID: 31254159

Brough HA, Nadeau KC, Sindher SB, Alkotob SS, Chan S, Bahnson H, Leung DYM, Lack G. Epicutaneous sensitization in the development of food allergy: what is the evidence and how can this be prevented? Allergy. 2020 Apr 6. doi: 10.1111/all.14304. Review. PMID: 32249942 | PMC7494573

Bruchez A, Sha K, Johnson J, Chen L, Stefani C, McConnell H, Gaucherand L, Prins R, Matreyek KA, Hume AJ, Mühlberger E, Schmidt EV, Olinger GG, Stuart LM, Lacy-Hulbert A. MHC class II transactivator CIITA induces cell resistance to Ebola virus and SARS-like coronaviruses. Science. 2020 Oct 9;370(6513):241-247. doi: 10.1126/science.abb3753. Epub 2020 Aug 27. PMID: 32855215 | PMC7665841

Bukiri H, Ruhoy SM, Buckner JH. Sudden Cardiac Death due to Coronary Artery Vasculitis in a Patient with Relapsing Polychondritis. Case Rep Rheumatol. 2020 Nov 16;2020:5620471. doi: 10.1155/2020/5620471. PMID: 33282427 | PMC7685837

Campbell VL, Nguyen L, Snoey E, McClurkan CL, Laing KJ, Dong L, Sette A, Lindestam Arlehamn CS, Altmann DM, Boyton RJ, Roby JA, Gale M Jr, Stone M, Busch MP, Norris PJ, Koelle DM. Proteome-Wide Zika Virus CD4 T Cell Epitope and HLA Restriction Determination. Immunohorizons. 2020 Aug 4;4(8):444-453. doi: 10.4049/immunohorizons.2000068. PMID: 32753403 | PMC7839664

Carmona-Rivera C, Carlucci PM, Goel RR, James EA, Brooks SR, Rims CR, Hoffmann V, Fox DA, Buckner JH, Kaplan MJ. Neutrophil Extracellular Traps Mediate Articular Cartilage Damage and Enhance Cartilage Component Immunogenicity in Rheumatoid Arthritis. 2020 Jul 9;5(13):139388. doi: 10.1172/jci.insight.139388. PMID: 32484790 | PMC7406272

Carmona-Rivera C, Carlucci PM, Moore E, Lingampalli N, Uchtenhagen H, James E, Liu Y, Bicker KL, Wahamaa H, Hoffmann V, Catrina AI, Thompson PR, Buckner JH, Robinson WH, Fox DA, Kaplan MJ. Erratum for Research Article "Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis" by C. Carmona-Rivera, P. M. Carlucci, E. Moore, N. Lingampalli, H. Uchtenhagen, E. James, Y. Liu, K. L. Bicker, H. Wahamma, V. Hoffman, A. I. Catrina, P. Thompson, J. H. Buckner, W. H. Robinson, D. A. Fox, M. J. Kaplan. Sci Immunol. 2020 Jan 31;5(43):eaaz9319. doi: 10.1126/sciimmunol.aaz9319. Erratum for: Sci Immunol. 2017 Apr;2(10): PMID: 32005681 | PMC7228189

Caumont F, Porter C, DeBerg H, Burns J, Frankel J, Flores JP. Combined chemotherapy and radiotherapy improves survival in 1897 testicular Lymphoma patients from a contemporary cohort. Urol Oncol. 2020 Apr 16. pii: S1078-1439(20)30082-X. doi: 10.1016/j.urolonc.2020.02.027. PMID: 32307328

Chen AC, Cai X, Li C, Khoryati L, Gavin MA, Miao CH. A Treg-Selective IL-2 Mutein Prevents the Formation of Factor VIII Inhibitors in Hemophilia Mice Treated With Factor VIII Gene Therapy. Front Immunol . 2020 Apr 28;11:638. doi: 10.3389/fimmu.2020.00638. eCollection 2020. PMID: 32411127 | PMC7198749

Cook L, Rees WD, Wong MQ, Kwok WW, Levings MK, Steiner TS. Recurrent Clostridioides difficile infection is associated with impaired Th17 immunity to TcdB. Gastroenterology. 2020 Nov 27;S0016-5085(20)35510-4. doi: 10.1053/j.gastro.2020.11.043. PMID: 33253683

Cortez FJ, Gebhart D, Robinson PV, Seftel D, Pourmandi N, Owyoung J, Bertozzi CR, Wilson DM, Maahs DM, Buckingham BA, Mills JR, Roforth MM, Pittock SJ, McKeon A, Page K, Wolf WA, Sanda S, Speake C, Greenbaum CJ, Tsai CT. Sensitive detection of multiple islet autoantibodies in type 1 diabetes using small sample volumes by agglutination-PCR. PLoS One. 2020 Nov 13;15(11):e0242049. doi: 10.1371/journal.pone.0242049. PMID: 33186361 | PMC7665791

Damodarasamy M, Vernon RB, Pathan JL, Keene CD, Day AJ, Banks WA, Reed MJ. The microvascular extracellular matrix in brains with Alzheimer's disease neuropathologic change (ADNC) and cerebral amyloid angiopathy (CAA). Fluids Barriers CNS. 2020 Sep 29;17(1):60. doi: 10.1186/s12987-020-00219-y. PMID: 32993718 | PMC7525948

DeGottardi Q, Gates TJ, Yang J, James EA, Malhotra U, Chow IT, Simoni Y, Fehlings M, Newell EW, DeBerg HA, Kwok WW. Ontogeny of different subsets of yellow fever virus-specific circulatory CXCR5+ CD4+ T cells after yellow fever vaccination. Sci Rep. 2020 Sep 24;10(1):15686. doi: 10.1038/s41598-020-72610-6. PMID: 32973217 | PMC7519049

Di Fulvio M, Bogdani M, Velasco M, McMillen TS, Ridaura C, Kelly L, Almutairi MM, Kursan S, Sajib AA, Hiriart M, Aguilar-Bryan L. Heterogeneous expression of CFTR in insulin-secreting β-cells of the normal human islet. PLoS One  2020 Dec 2;15(12):e0242749. doi: 10.1371/journal.pone.0242749. eCollection 2020. PMID: 33264332 | PMC7710116

Diggins KE, Serti E, Muir VS, Rosasco MG, Lu T, Balmas E, Nepom GT, Long SA, Linsley PS. Exhausted-like CD8 T cell phenotypes linked to C-peptide preservation in alefacept-treated T1D subjects. JCI Insight. 2020 Dec 22;142680. doi: 10.1172/jci.insight.142680. PMID: 33351781 | PMC7934874

Evanko SP, Gooden MD, Kang I, Chan CK, Vernon RB, Wight TN. A Role for HAPLN1 During Phenotypic Modulation of Human Lung Fibroblasts In Vitro. J Histochem Cytochem. 2020 Oct 16:22155420966663. doi: 10.1369/0022155420966663. PMID: 33064036 | PMC7649966

Fisher HR, Lack G, Roberts G, Bahnson HT, Du Toit G. Medical Algorithm: Early Introduction of Food Allergens in High Risk Populations. Allergy 2020 Dec 21. doi: 10.1111/all.14717. PMID: 33346913

Gerstner C, Turcinov S, Hensvold AH, Chemin K, Uchtenhagen H, Ramwadhdoebe TH, Dubnovitsky A, Kozhukh G, Rönnblom L, Kwok WW, Achour A, Catrina AI, van Baarsen LGM, Malmström V. Multi-HLA class II tetramer analyses of citrulline-reactive T cells and early treatment response in rheumatoid arthritis. BMC Immunol. 2020 May 18;21(1):27. doi: 10.1186/s12865-020-00357-w. PMID: 32423478 | PMC7236297

Glatigny S, Höllbacher B, Motley SJ, Tan C, Hundhausen C, Buckner JH, Smilek D, Khoury SJ, Ding L, Qin T, Pardo J, Nepom GT, Turka LA, Harris KM, Campbell DJ, Bettelli E. Abatacept Targets T Follicular Helper and Regulatory T Cells, Disrupting Molecular Pathways That Regulate Their Proliferation and Maintenance. J Immunol 2019 Mar 1;202(5):1373-1382. doi: 10.4049/jimmunol.1801425. Epub 2019 Jan 25. PMID: 30683697 | PMC6481683

Gratz IK, Campbell DJ. Resident memory T cells show that it is never too late to change your ways. Nat Immunol. 2020 Apr;21(4):359-360. doi: 10.1038/s41590-020-0637-1. PMID: 32205885

Han CY, Kang I, Harten IA, Gebe JA, Chan CK, Omer M, Alonge KM, den Hartigh LJ, Gomes Kjerulf D, Goodspeed L, Subramanian S, Wang S, Kim F, Birk DE, Wight TN, Chait A. Adipocyte-Derived Versican and Macrophage-Derived Biglycan Control Adipose Tissue Inflammation in Obesity. Cell Rep. 2020 Jun 30;31(13):107818. doi: 10.1016/j.celrep.2020.107818. PMID: 32610121 | PMC7384517

Han CY, Kang I, Omer M, Wang S, Wietecha T, Wight TN, Chait A. Serum amyloid A-containing HDL binds adipocyte-derived versican and macrophage-derived biglycan,reducing its antiinflammatory properties. JCI Insight. 2020 Sep 24;5(20):142635. doi: 10.1172/jci.insight.142635. PMID: 32970631 | PMC7605543

Harrison O. Poised for tissue repair. Science. 2020 Jul 10;369(6500):152-153. doi: 10.1126/science.abc5618. PMID: 32646993

Harten IA, Kaber G, Agarwal KJ, Kang I, Ibarrientos SR, Workman G, Chan CK, Nivison MP, Nagy N, Braun KR, Kinsella MG, Merrilees MJ, Wight TN. The Synthesis and Secretion of Versican Isoform V3 by Mammalian Cells: A Role for N-linked Glycosylation. Matrix Biol. 2020 Jan 27. pii: S0945-053X(20)30008-1. doi: 10.1016/j.matbio.2020.01.002. PMID: 32001344 | PMC7282976

Hayes ET, Hagan CE, Khoryati L, Gavin MA, Campbell DJ. Regulatory T Cells Maintain Selective Access to IL-2 and Immune Homeostasis despite Substantially Reduced CD25 Function. J Immunol. 2020 Oct 14:ji1901520. doi: 10.4049/jimmunol.1901520. PMID: 33055282 | PMC7657993

Höllbacher B, Duhen T, Motley S, Klicznik MM, Gratz IK, Campbell DJ. Transcriptomic Profiling of Human Effector and Regulatory T Cell Subsets Identifies Predictive Population Signatures. Immunohorizons. 2020 Oct 9;4(10):585-596. doi: 10.4049/immunohorizons.2000037. PMID: 33037096 | PMC8085975

Honaker Y, Hubbard N, Xiang Y, Fisher L, Hagin D, Sommer K, Song Y, Yang SJ, Lopez C, Tappen T, Dam EM, Khan I, Hale M, Buckner JH, Scharenberg AM, Torgerson TR, Rawlings DJ. Gene Editing to Induce FOXP3 Expression in Human CD4 + T Cells Leads to a Stable Regulatory Phenotype and Function. Sci Transl Med . 2020 Jun 3;12(546):eaay6422. doi: 10.1126/scitranslmed.aay6422. PMID: 32493794

Hurabielle C, Link VM, Bouladoux N, Han SJ, Merrill ED, Lightfoot YL, Seto N, Bleck CKE, Smelkinson M, Harrison OJ, Linehan JL, Tamoutounour S, Lionakis MS, Kaplan MJ, Nakajima S, Belkaid Y. Immunity to Commensal Skin Fungi Promotes Psoriasiform Skin Inflammation. Proc Natl Acad Sci U S A. 2020 Jun 29:202003022. doi: 10.1073/pnas.2003022117. PMID: 32601220 | PMC7368261

Jackson DJ, Busse WW, Bacharier LB, Kattan M, O'Connor GT, Wood RA, Visness CM, Durham SR, Larson D, Esnault S, Ober C, Gergen PJ, Becker P, Togias A, Gern JE, Altman MC. Association of Respiratory Allergy, Asthma and Expression of the SARS-CoV-2 Receptor, ACE2. J Allergy Clin Immunol. 2020 Apr 22. pii: S0091-6749(20)30551-0. doi: 10.1016/j.jaci.2020.04.009. PMID: 32333915 | PMC7175851

Jackson DJ, Busse WW, Togias A, Gern JE, Altman MC. Reply. J Allergy Clin Immunol. 2020 Aug 14:S0091-6749(20)31103-9. doi: 10.1016/j.jaci.2020.07.028. PMID: 32828589 | PMC7427546

James EA, Mallone R, Kent SC, DiLorenzo TP. T-Cell Epitopes and Neo-epitopes in Type 1 Diabetes: A Comprehensive Update and Reappraisal. JCI Insight. 2020 Jun 23:136579. doi: 10.1172/jci.insight.136579. PMID: 32561620 | PMC7306130

Kabata H, Flamar AL, Mahlakõiv T, Moriyama S, Rodewald HR, Ziegler SF, Artis D. Targeted deletion of the TSLP receptor reveals cellular mechanisms that promote type 2 airway inflammation. Mucosal Immunol. 2020 Feb 17. doi: 10.1038/s41385-020-0266-x. PMID: 32066836 | PMC7311324

Keating SM, Waltemath D, König M, Zhang F, Dräger A, Chaouiya C, Bergmann FT, Finney A, Gillespie CS, Helikar T, Hoops S, Malik-Sheriff RS, Moodie SL, Moraru II, Myers CJ, Naldi A, Olivier BG, Sahle S, Schaff JC, Smith LP, Swat MJ, Thieffry D, Watanabe L, Wilkinson DJ, Blinov ML, Begley K, Faeder JR, Gómez HF, Hamm TM, Inagaki Y, Liebermeister W, Lister AL, Lucio D, Mjolsness E, Proctor CJ, Raman K, Rodriguez N, Shaffer CA, Shapiro BE, Stelling J, Swainston N, Tanimura N, Wagner J, Meier-Schellersheim M, Sauro HM, Palsson B, Bolouri H, Kitano H, Funahashi A, Hermjakob H, Doyle JC, Hucka M; SBML Level 3 Community members. SBML Level 3: an extensible format for the exchange and reuse of biological models. Mol Syst Biol. 2020 Aug;16(8):e9110. doi: 10.15252/msb.20199110. PMID: 32845085

Kellar GG, Barrow KA, Rich LM, Debley JS, Wight TN, Ziegler SF, Reeves SR. Loss of versican and production of hyaluronan in lung epithelial cells are associated with airway inflammation during RSV infection. J Biol Chem. 2020 Nov 13:jbc.RA120.016196. doi: 10.1074/jbc.RA120.016196. PMID: 33187989 | PMC7949086

Kellar GG, Reeves SR, Barrow KA, Debley JS, Wight TN, Ziegler SF. Juvenile, but Not Adult, Mice Display Increased Myeloid Recruitment and Extracellular Matrix Remodeling during Respiratory Syncytial Virus Infection. J Immunol. 2020 Dec 1;205(11):3050-3057. doi: 10.4049/jimmunol.2000683. Epub 2020 Oct 23. PMID: 33097575 | PMC7747670

Khoryati L, Pham MN, Sherve M, Kumari S, Cook K, Pearson J, Bogdani M, Campbell DJ, Gavin MA. An IL-2 mutein engineered to promote expansion of regulatory T cells arrests ongoing autoimmunity in mice. Sci Immunol. 2020 Aug 14;5(50):eaba5264. doi: 10.1126/sciimmunol.aba5264. PMID: 32817295 | PMC7643170

Kitajima M, Kubo M, Ziegler SF, Suzuki H. Critical Role of TSLP Receptor on CD4 T Cells for Exacerbation of Skin Inflammation. J Immunol . 2020 May 22;ji1900758. doi: 10.4049/jimmunol.1900758. PMID: 32444388

Klicznik MM, Benedetti A, Gail LM, Varkhande SR, Holly R, Laimer M, Stoecklinger A, Sir A, Reitsamer R, Neuper T, Horejs-Hoeck J, Rosenblum MD, Campbell DJ, Murauer EM, Gratz IK. A novel humanized mouse model to study the function of human cutaneous memory T cells in vivo in human skin. Sci Rep 2020 Jul 7;10(1):11164. doi: 10.1038/s41598-020-67430-7. PMID: 32636404 | PMC7341892

Lai JF, Thompson LJ, Ziegler SF. TSLP drives acute Th2 differentiation in lungs. J Allergy Clin Immunol. 2020 Apr 15. pii: S0091-6749(20)30484-X. doi: 10.1016/j.jaci.2020.03.032. PMID: 32304753 | PMC7572459

Lande R, Palazzo R, Gestermann N, Jandus C, Falchi M, Spadaro F, Riccieri V, James EA, Butera A, Boirivant M, Feldmeyer L, Surbeck I, Di Lucca J, Stuber F, Spinelli FR, Botti E, Marinari B, Bianchi L, Pica R, Cerbelli B, Giannakakis K, Auteri SE, Daniels I, Durrant LG, Horstman S, Costanzo A, Romero P, Alessandri C, Conti F, Valesini G, Gilliet M, Chizzolini C, Frasca L. Native/citrullinated LL37-specific T-cells help autoantibody production in Systemic Lupus Erythematosus. Sci Rep. 2020 Apr 3;10(1):5851. doi: 10.1038/s41598-020-62480-3. PMID: 32245990 | PMC7125190

Larson D, Patel P, Salapatek AM, Couroux P, Whitehouse D, Pina A, Johnson JL, Sever ML, Sanda S, Poyser J, Allio T, Scadding GW, Qin T, Shamji MH, Kwok WW, James EA, French D, Lelic A, Larché M, Altman MC, Togias A, Durham SR. Nasal Allergen Challenge and Environmental Exposure Chamber Challenge: A Randomized Trial Comparing Clinical and Biological Responses to Cat Allergen. J Allergy Clin Immunol. 2020 Jun;145(6):1585-1597. doi: 10.1016/j.jaci.2020.02.024. Epub 2020 Mar 10. PMID: 32169380

Leonard MM, Silvester JA, Leffler D, Fasano A, Kelly CP, Lewis SK, Goldsmith JD, Greenblatt E, Kwok WW, McAuliffe WJ, Galinsky K, Siegelman J, Chow IT, Wagner JA, Sapone A, Smithson G. Evaluating Responses to Gluten Challenge: A Randomized, Double-Blind, 2-Dose Gluten Challenge Trial. Gastroenterology. 2020 Oct 29:S0016-5085(20)35330-0. doi: 10.1053/j.gastro.2020.10.040. PMID: 33130104 | PMC7878429

Leyva-Castillo JM, Galand C, Mashiko S, Bissonnette R, McGurk A, Ziegler SF, Dong C, McKenzie ANJ, Sarfati M, Geha RS. ILC2 activation by keratinocyte-derived IL-25 drives IL-13 production at sites of allergic skin inflammation. J Allergy Clin Immunol. 2020 Jun;145(6):1606-1614.e4. doi: 10.1016/j.jaci.2020.02.026. Epub 2020 Mar 14. PMID: 32179159 | PMC7282942

Li D, Matta B, Song S, Nelson V, Diggins K, Simpfendorfer KR, Gregersen PK, Linsley P, Barnes BJ. IRF5 genetic risk variants drive myeloid-specific IRF5 hyperactivation and presymptomatic SLE. JCI Insight. 2020 Jan 30;5(2). pii: 124020. doi: 10.1172/jci.insight.124020. PMID: 31877114 | PMC7098722

Logan K, Perkin MR, Marrs T, Radulovic S, Craven J, Flohr C, Bahnson HT, Lack G. Early Gluten Introduction and Celiac Disease in the EAT Study: A Prespecified Analysis of the EAT Randomized Clinical Trial. JAMA Pediatr. 2020 Sep 28:e202893. doi: 10.1001/jamapediatrics.2020.2893. PMID: 32986087 | PMC7522778

Lord S, Greenbaum CJ. Insulin is necessary but not sufficient: changing the therapeutic paradigm in type 1 diabetes. F1000Res. 2020 Jul 30;9:F1000 Faculty Rev-827. doi: 10.12688/f1000research.21801.1. PMID: 32789003 | PMC7400689

Luo J, Weaver MS, Fitzgibbons TP, Aouadi M, Czech MP, Allen MD. Immunotherapy for Infarcts: In Vivo Postinfarction Macrophage Modulation Using Intramyocardial Microparticle Delivery of Map4k4 Small Interfering RNA. Biores Open Access 2020 Dec 2;9(1):258-268. doi: 10.1089/biores.2020.0037. eCollection 2020. PMID: 33376632 | PMC7757732

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