2018 Publications

The following list highlights BRI's 2018 publications. More selective listings of publications are also included on scientist biography pages. Featured BRI Principal Investigators are listed in bold.

  1. Altman MC, Gern JE. Reply. J Allergy Clin Immunol. 2018 Jun 23. pii: S0091-6749(18)30766-8. doi: 10.1016/j.jaci.2018.04.035. No abstract available. PMID: 29945814

  2. Altman MC, Whalen E, Togias A, O'Connor GT, Bacharier LB, Bloomberg GR, Kattan M, Wood RA, Presnell S, LeBeau P, Jaffee K, Visness CM, Busse WW, Gern JE. Allergen-induced activation of natural killer cells represents an early-life immune response in the development of allergic asthma. J Allergy Clin Immunol. 2018 Mar 5. pii: S0091-6749(18)30307-5. doi: 10.1016/j.jaci.2018.02.019. PMID: 29518416

  3. Bingley PJ, Wherrett DK, Shultz A, Rafkin LE, Atkinson MA, Greenbaum CJ. Type 1 Diabetes TrialNet: A Multifaceted Approach to Bringing Disease-Modifying Therapy to Clinical Use in Type 1 Diabetes. Diabetes Care. 2018 Apr;41(4):653-661. doi: 10.2337/dc17-0806. PMID: 29559451 | PMC5860837

  4. Birrueta G, Tripple V, Pham J, Manohar M, James EA, Kwok WW, Nadeau KC, Sette A, Peters B, Schulten V. Peanut-specific T cell responses in patients with different clinical reactivity. PLoS One. 2018 Oct 10;13(10):e0204620. doi: 10.1371/journal.pone.0204620. eCollection 2018. PMID: 30304054 | PMC6179248

  5. Blahnik G, Uchtenhagen H, Chow IT, Speake C, Greenbaum C, Kwok WW, James EA. Analysis of pancreatic beta cell specific CD4+ T cells reveals a predominance of proinsulin specific cells. Cell Immunol. 2018 Nov 7. pii: S0008-8749(18)30273-9. doi: 10.1016/j.cellimm.2018.11.004. PMID: 30428974

  6. Boden EK, Shows DM, Chiorean MV, Lord JD. Identification of Candidate Biomarkers Associated with Response to Vedolizumab in Inflammatory Bowel Disease. Dig Dis Sci. 2018 Jan 25. doi: 10.1007/s10620-018-4924-8. PMID: 29372476

  7. Boonpiyathad T, Sokolowska M, Morita H, Rückert B, Kast JI, Wawrzyniak M, Sangasapaviliya A, Pradubpongsa P, Fuengthong R, Thantiworasit P, Sirivichayakul S, Kwok WW, Ruxrungtham K, Akdis M, Akdis CA. Der p 1-specific regulatory T cell response during house dust mite allergen immunotherapy. Allergy. 2018 Nov 28. doi: 10.1111/all.13684. PMID: 30485456

  8. Buitinga M, Callebaut A, Marques Câmara Sodré F, Crèvecoeur I, Blahnik-Fagan G, Yang ML, Bugliani M, Arribas-Layton D, Marré M, Cook DP, Waelkens E, Mallone R, Piganelli JD, Marchetti P, Mamula MJ, Derua R, James EA, Mathieu C, Overbergh L. Inflammation-Induced Citrullinated Glucose-Regulated Protein 78 Elicits Immune Responses in Human Type 1 Diabetes. Diabetes. 2018 Nov;67(11):2337-2348. doi: 10.2337/db18-0295. PMID: 30348823

  9. Cabrera SM, Engle S, Kaldunski M, Jia S, Geoffrey R, Simpson P, Szabo A, Speake C, Greenbaum CJ; Type 1 Diabetes TrialNet CTLA4-Ig (Abatacept) Study Group, Chen YG, Hessner MJ. Innate immune activity as a predictor of persistent insulin secretion and association with responsiveness to CTLA4-Ig treatment in recent-onset type 1 diabetes. Diabetologia. 2018 Nov;61(11):2356-2370. doi: 10.1007/s00125-018-4708-x. Epub 2018 Aug 30. PMID: 30167736 | PMC6182660

  10. Carmona-Rivera C, Bicker KL, Thompson PR, Buckner JH, Robinson WH, Fox DA, Kaplan MJ. Response to comment on "Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis". Sci Immunol. 2018  Mar 30;3(21). pii: eaar3701. doi: 10.1126/sciimmunol.aar3701. PMID: 29602804

  11. Couper JJ, Haller MJ, Greenbaum CJ, Ziegler AG, Wherrett DK, Knip M, Craig ME. ISPAD Clinical Practice Consensus Guidelines 2018 Stages of type 1 diabetes in children and adolescents. Pediatr Diabetes. 2018 Jul 26. doi: 10.1111/pedi.12734. PMID: 30051639

  12. Culina S, Lalanne AI, Afonso G, Cerosaletti K, Pinto S, Sebastiani G, Kuranda K, Nigi L, Eugster A, Østerbye T, Maugein A, McLaren JE, Ladell K, Larger E, Beressi JP, Lissina A, Appay V, Davidson HW, Buus S, Price DA, Kuhn M, Bonifacio E, Battaglia M, Caillat-Zucman S, Dotta F, Scharfmann R, Kyewski B, Mallone R; ImMaDiab Study Group, Carel JC, Tubiana-Rufi N, Martinerie L, Poidvin A, JacqzAigrain E, Corvez L, Berruer V, Gautier JF, Baz B, Haddadi N, Andreelli F, Amouyal C, Jaqueminet S, Bourron O, Dasque E, Hartemann A, Lemoine-Yazigi A, Dubois-Laforgue D, Travert F, Feron M, Rolland P, Vignali V, Marre M, Chanson P, Briet C, Guillausseau PJ, Ait-Bachir L, Collet C, Beziaud F, Desforges-Bullet V, Petit-Aubert G, Christin-Maitre S, Fève B, Vatier C, Bourcigaux N, Lautridou C, Lahlou N, Bakouboula P, Elie C, Morel H, Treluyer JM, Gagnerault MC, Maillard C, Jones A. Islet-reactive CD8(+) T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors. Sci Immunol. 2018 Feb 2;3(20). pii: eaao4013. doi: 10.1126/sciimmunol.aao4013. PMID: 29429978 | PMC5874133

  13. Dam EM, Maier AC, Hocking AM, Carlin J, Buckner JH. Increased Binding of Specificity Protein 1 to the IL21R Promoter in B Cells Results in Enhanced B Cell Responses in Rheumatoid Arthritis. Front Immunol. 2018 Sep 5;9:1978. doi: 10.3389/fimmu.2018.01978. eCollection 2018. PMID: 30233580 | PMC6134023

  14. DeBerg HA, Zaidi MB, Altman MC, Khaenam P, Gersuk VH, Campos FD, Perez-Martinez I, Meza-Segura M, Chaussabel D, Banchereau J, Estrada-Garcia T, Linsley PS. Shared and organism-specific host responses to childhood diarrheal diseases revealed by whole blood transcript profiling. PLoS One. 2018 Jan 29;13(1):e0192082. doi: 10.1371/journal.pone.0192082. eCollection 2018. PMID: 29377961 | PMC5788382

  15. Du J, Wang Q, Ziegler SF, Zhou B. FOXP3 interacts with hnRNP F to modulate pre-mRNA alternative splicing. J Biol Chem. 2018 May 17. pii: jbc.RA117.001349. doi: 10.1074/jbc.RA117.001349. PMID: 29773655 | PMC6028976

  16. Ettinger RA, Liberman JA, Gunasekera D, Puranik K, James EA, Thompson AR, Pratt KP. FVIII proteins with a modified immunodominant T-cell epitope exhibit reduced immunogenicity and normal FVIII activity. Blood Adv. 2018 Feb 27;2(4):309-322. doi: 10.1182/bloodadvances.2017013482. PMID: 29444872 | PMC5858479

  17. Evanko SP, Chan CK, Johnson PY, Frevert CW, Wight TN. The biochemistry and immunohistochemistry of versican. Methods Cell Biol. 2018;143:261-279. doi: 10.1016/bs.mcb.2017.08.015. Epub 2017 Nov 26. PMID: 29310782

  18. Fisher H, Toit GD, Bahnson HT, Lack G. The Challenges of Preventing Food Allergy: lessons learned from LEAP and EAT. Ann Allergy Asthma Immunol. 2018 Jun 14. pii: S1081-1206(18)30468-X. doi: 10.1016/j.anai.2018.06.008. Review. PMID: 29909054

  19. Gebe JA, Preisinger A, Gooden MD, D'Amico LA, Vernon RB. Local, Controlled Release In Vivo of Vascular Endothelial Growth Factor Within a Subcutaneous Scaffolded Islet Implant Reduces Early Islet Necrosis and Improves Performance of the Graft. Cell Transplant. 2018 Mar;27(3):531-541. doi: 10.1177/0963689718754562. Epub 2018 May 14. PMID: 29756517 | PMC6038045

  20. Glatigny S, Bettelli E. Experimental Autoimmune Encephalomyelitis (EAE) as Animal Models of Multiple Sclerosis (MS). Cold Spring Harb Perspect Med. 2018 Jan 8. pii: a028977. doi: 10.1101/cshperspect.a028977. PMID: 29311122

  21. Goddard TD, Brilliant AA, Skillman TL, Vergenz S, Tyrwhitt-Drake J, Meng EC, Ferrin TE. Molecular Visualization on the Holodeck. J Mol Biol. 2018 Jun 28. pii: S0022-2836(18)30696-X. doi: 10.1016/j.jmb.2018.06.040. PMID: 29964044 | PMC6223615

  22. Greenbaum CJ, Speake C, Krischer J, Buckner J, Gottlieb PA, Schatz DA, Herold KC, Atkinson MA. Strength in Numbers: Opportunities for Enhancing the Development of Effective Treatments for Type 1 Diabetes-The TrialNet Experience. Diabetes. 2018 May 16. pii: db180065. doi: 10.2337/db18-0065. PMID: 29769238 | PMC6014559

  23. Hahn WO, Butler NS, Lindner SE, Akilesh HM, Sather DN, Kappe SH, Hamerman JA, Gale M Jr., Liles WC, Pepper M. cGAS-mediated control of blood-stage malaria promotes Plasmodium-specific germinal center responses. JCI Insight. 2018 Jan 25;3(2). pii: 94142. doi: 10.1172/jci.insight.94142. PMID: 29367469 | PMC5821207

  24. Han H, Roan F, Johnston LK, Smith DE, Bryce PJ, Ziegler SF. IL-33 promotes gastrointestinal allergy in a TSLP-independent manner. Mucosal Immunol. 2018 Mar;11(2):394-403. doi: 10.1038/mi.2017.61. Epub 2017 Jun 28. Erratum in: Mucosal Immunol. 2017 Oct 25. PMID: 28656964 | PMC5745299

  25. Holers VM, Demoruelle MK, Kuhn KA, Buckner JH, Robinson WH, Okamoto Y, Norris JM, Deane KD. Rheumatoid arthritis and the mucosal origins hypothesis: protection turns to destruction. Nat Rev Rheumatol. 2018 Sep;14(9):542-557. doi: 10.1038/s41584-018-0070-0. PMID: 30111803

  26. James EA, Abreu JRF, McGinty JW, Odegard JM, Fillié YE, Hocter CN, Culina S, Ladell K, Price DA, Alkanani A, Rihanek M, Fitzgerald-Miller L, Skowera A, Speake C, Gottlieb P, Davidson HW, Wong FS, Roep B, Mallone R; Immunology of Diabetes Society T Cell Workshop Committee. Combinatorial detection of autoreactive CD8(+) T cells with HLA-A2 multimers: a multi-centre study by the Immunology of Diabetes Society T Cell Workshop. Diabetologia. 2018 Mar;61(3):658-670. doi:10.1007/s00125-017-4508-8. Epub 2017 Dec 1. PMID: 29196783

  27. James EA, Gillette L, Durinovic-Bello I, Speake C, Bondinas GP, Moustakas AK, Greenbaum CJ, Papadopoulos GK, Kwok WW. DRB4*01:01 Has a Distinct Motif and Presents a Proinsulin Epitope That Is Recognized in Subjects with Type 1 Diabetes. J Immunol. 2018 Nov 19. pii: ji1800723. doi: 10.4049/jimmunol.1800723. PMID: 30455401 | PMC6426329

  28. James EA, Pietropaolo M, Mamula MJ. Immune Recognition of β-Cells: Neoepitopes as Key Players in the Loss of Tolerance. Diabetes. 2018 Jun;67(6):1035-1042. doi: 10.2337/dbi17-0030. PMID: 29784651 | PMC5961411

  29. Jones BE, Maerz MD, Buckner JH. IL-6: a cytokine at the crossroads of autoimmunity. Curr Opin Immunol. 2018 Sep 21;55:9-14. doi: 10.1016/j.coi.2018.09.002. Review. PMID: 30248523 | PMC6286200

  30. Kang I, Chang MY, Wight TN, Frevert CW. Proteoglycans as Immunomodulators of  the Innate Immune Response to Lung Infection. J Histochem Cytochem. 2018 Apr;66(4):241-259. doi: 10.1369/0022155417751880. Epub 2018 Jan 12. PMID: 29328866 | PMC5958380

  31. Kanter JE, Kramer F, Barnhart S, Duggan JM, Shimizu-Albergine M, Kothari V, Chait A, Bouman SD, Hamerman JA, Hansen BF, Olsen GS, Bornfeldt KE. A Novel Strategy to Prevent Advanced Atherosclerosis and Lower Blood Glucose in a Mouse Model of Metabolic Syndrome. Diabetes. 2018 Feb 26. pii: db170744. doi: 10.2337/db17-0744. PMID: 29483182 | PMC5909997

  32. Kenagy RD, Kikuchi S, Evanko SP, Ruiter MS, Piola M, Longchamp A, Pesce M, Soncini M, Deglise S, Fiore GB, Haefliger JA, Schmidt TA, Majesky MW, Sobel M, Wight TN. Versican is differentially regulated in the adventitial and medial layers of human vein grafts. PLoS One. 2018 Sep 28;13(9):e0204045. doi: 10.1371/journal.pone.0204045. eCollection 2018. PMID: 30265729 | PMC6161854

  33. Kikuchi S, Chen L, Xiong K, Saito Y, Azuma N, Tang G, Sobel M, Wight TN, Kenagy RD. Smooth muscle cells of human veins show an increased response to injury at valve sites. J Vasc Surg. 2018 May;67(5):1556-1570.e9. doi: 10.1016/j.jvs.2017.03.447. Epub 2017 Jun 21. PMID: 28647196 | PMC5740028

  34. Kimura T, Kobiyama K, Winkels H, Tse K, Miller J, Vassallo M, Wolf D, Ryden C, Orecchioni M, Dileepan T, Jenkins MK, James EA, Kwok WW, Hanna DB, Kaplan RC, Strickler HD, Durkin HG, Kassaye SG, Karim R, Tien PC, Landay AL, Gange SJ, Sidney J, Sette A, Ley K. Regulatory CD4(+) T Cells Recognize MHC-II-Restricted Peptide Epitopes of Apolipoprotein B. Circulation. 2018 Mar 27. pii:CIRCULATIONAHA.117.031420. doi: 10.1161/CIRCULATIONAHA.117.031420. PMID: 29588316

  35. Klicznik MM, Szenes-Nagy AB, Campbell DJ, Gratz IK. Taking the lead - how keratinocytes orchestrate skin T cell immunity. Immunol Lett. 2018 Jun 30;200:43-51. doi: 10.1016/j.imlet.2018.06.009. Review. PMID: 29969603

  36. Konnikova L, Boschetti G, Rahman A, Mitsialis V, Lord J, Richmond C, Tomov VT, Gordon W, Jelinsky S, Canavan J, Liss A, Wall S, Field M, Zhou F, Goldsmith JD, Bewtra M, Breault DT, Merad M, Snapper SB. High-dimensional immune phenotyping and transcriptional analyses reveal robust recovery of viable human immune and epithelial cells from frozen gastrointestinal tissue. Mucosal Immunol. 2018 Aug 15. doi: 10.1038/s41385-018-0047-y. PMID: 30111863

  37. Kuan EL, Ziegler SF. A tumor-myeloid cell axis, mediated via the cytokines IL-1α and TSLP, promotes the progression of breast cancer. Nat Immunol. 2018 Apr;19(4):366-374. doi: 10.1038/s41590-018-0066-6. Epub 2018 Mar 19. PMID: 29556001 | PMC5864553

  38. Kulis MD, Patil SU, Wambre E, Vickery BP. Immune mechanisms of oral immunotherapy. J Allergy Clin Immunol. 2018 Feb;141(2):491-498. doi: 10.1016/j.jaci.2017.12.979. Epub 2017 Dec 26. PMID: 29288078

  39. Lacher MD, Bauer G, Fury B, Graeve S, Fledderman EL, Petrie TD, Coleal-Bergum DP, Hackett T, Perotti NH, Kong YY, Kwok WW, Wagner JP, Wiseman CL, Williams WV. SV-BR-1-GM, a Clinically Effective GM-CSF-Secreting Breast Cancer Cell Line, Expresses an Immune Signature and Directly Activates CD4+ T Lymphocytes. Front Immunol. 2018 May 15;9:776. doi: 10.3389/fimmu.2018.00776. eCollection 2018. PMID: 29867922 | PMC5962696

  40. Linsley PS, Greenbaum CJ, Rosasco M, Presnell S, Herold KC, Dufort MJ. Elevated T cell levels in peripheral blood predict poor clinical response following rituximab treatment in new-onset type 1 diabetes. Genes Immun. 2018 Jun 21. doi: 10.1038/s41435-018-0032-1. Genes Immun. 2018 Jun 21. doi: 10.1038/s41435-018-0032-1. PMID: 29925930

  41. Lord JD, Long SA, Shows DM, Thorpe J, Schwedhelm K, Chen J, Kita M, Buckner JH. Circulating integrin alpha4/beta7+ lymphocytes targeted by vedolizumab have a pro-inflammatory phenotype. Clin Immunol. 2018 May 26;193:24-32. doi: 10.1016/j.clim.2018.05.006. PMID: 29842945

  42. Maisel K, Merrilees MJ, Atochina-Vasserman EN, Lian L, Obraztsova K, Rue R, Vasserman AN, Zuo N, Angel LF, Gow AJ, Kang I, Wight TN, Eruslanov E, Swartz MA, Krymskaya VP. Immune Checkpoint Ligand PD-L1 is Upregulated in Pulmonary Lymphangioleiomyomatosis (LAM). Am J Respir Cell Mol Biol. 2018 Aug 10. doi: 10.1165/rcmb.2018-0123OC. PMID: 30095976 | PMC6293078

  43. Marre ML, McGinty JW, Chow IT, DeNicola ME, Beck NW, Kent SC, Powers AC, Bottino R, Harlan DM, Greenbaum CJ, Kwok WW, Piganelli JD, James EA. Modifying Enzymes are Elicited by ER Stress, Generating Epitopes that are Selectively Recognized by CD4+ T Cells in Patients With Type 1 Diabetes. Diabetes. 2018 Apr 13. pii: db171166. doi: 10.2337/db17-1166. PMID: 29654212 | PMC6014552

  44. Marré ML, Piganelli JD, James EA. Protecting functional β cells with a therapeutic peptide. Ann Transl Med. 2018 Sep;6(18):372. doi: 10.21037/atm.2018.07.26. No abstract available. PMID: 30370299 | PMC6186570

  45. Morrell ED, Wiedeman A, Long SA, Gharib SA, West TE, Skerrett SJ, Wurfel MM, Mikacenic C. Cytometry TOF identifies alveolar macrophage subtypes in acute respiratory distress syndrome. JCI Insight. 2018 May 17;3(10). pii: 99281. doi: 10.1172/jci.insight.99281. PMID: 29769438 | PMC6012519

  46. Muehling LM, Turner RB, Brown KB, Wright PW, Patrie JT, Lahtinen SJ, Lehtinen MJ, Kwok WW, Woodfolk JA. Single-Cell Tracking Reveals a Role for Pre-Existing CCR5+ Memory Th1 Cells in the Control of Rhinovirus-A39 After Experimental Challenge in Humans. J Infect Dis. 2018 Jan 17;217(3):381-392. doi: 10.1093/infdis/jix514. PMID: 29309618 | PMC5853408

  47. Murray C, Miwa H, Dhar M, Park DE, Pao E, Martinez J, Kaanumale S, Loghin E, Graf J, Rhaddassi K, Kwok WW, Hafler D, Puleo C, Di Carlo D. Unsupervised capture and profiling of rare immune cells using multi-directional magnetic ratcheting. Lab Chip. 2018 Jul 24. doi: 10.1039/c8lc00518d. PMID: 30039125 | PMC6095198

  48. Nagy N, de la Zerda A, Kaber G, Johnson PY, Hu KH, Kratochvil MJ, Yadava K, Zhao W, Cui Y, Navarro G, Annes JP, Wight TN, Heilshorn SC, Bollyky PL, Butte MJ. Hyaluronan content governs tissue stiffness in pancreatic islet inflammation. J Biol Chem. 2018 Jan 12;293(2):567-578. doi: 10.1074/jbc.RA117.000148. Epub 2017 Nov 28. PMID: 29183997 | PMC5767862

  49. Nagy N, Sunkari VG, Kaber G, Hasbun S, Lam DN, Speake C, Sanda S, McLaughlin TL, Wight TN, Long SR, Bollyky PL. Hyaluronan levels are increased systemically in human type 2 but not type 1 diabetes independently of glycemic control. Matrix Biol. 2018 Sep 6. pii: S0945-053X(18)30309-3. doi: 10.1016/j.matbio.2018.09.003. PMID: 30196101 | PMC6401354

  50. Newton RH, Shrestha S, Sullivan JM, Yates KB, Compeer EB, Ron-Harel N, Blazar BR, Bensinger SJ, Haining WN, Dustin ML, Campbell DJ, Chi H, Turka LA. Maintenance of CD4 T cell fitness through regulation of Foxo1. Nat Immunol. 2018 Jul 9. doi: 10.1038/s41590-018-0157-4. PMID: 29988091 | PMC6289177

  51. Nowak-Węgrzyn A, Lawson K, Masilamani M, Kattan J, Bahnson HT, Sampson HA. Increased Tolerance to Less Extensively Heat-Denatured (Baked) Milk Products in Milk-Allergic Children. J Allergy Clin Immunol Pract. 2018 Mar - Apr;6(2):486-495.e5. doi: 10.1016/j.jaip.2017.10.021. Epub 2017 Dec 7. PMID: 29226808 | PMC5881948

  52. Oukka M, Bettelli E. Regulation of lymphocyte trafficking in central nervous system autoimmunity. Curr Opin Immunol. 2018 Sep 27;55:38-43. doi: 10.1016/j.coi.2018.09.008. Review. PMID: 30268837 | PMC6286213

  53. Perkin MR, Bahnson HT, Logan K, Marrs T, Radulovic S, Craven J, Flohr C, Lack G. Association of Early Introduction of Solids With Infant Sleep: A Secondary Analysis of a Randomized Clinical Trial. JAMA Pediatr. 2018 Jul 9:e180739. doi: 10.1001/jamapediatrics.2018.0739. PMID: 29987321 | PMC6142923

  54. Pieper J, Dubnovitsky A, Gerstner C, James EA, Rieck M, Kozhukh G, Tandre K, Pellegrino  S, Gebe JA, Rönnblom L, Sandalova T, Kwok WW, Klareskog L, Buckner JH, Achour A, Malmström V. Memory T cells specific to citrullinated α-enolase are enriched in the rheumatic joint. J Autoimmun. 2018 May 28. pii: S0896-8411(18)30128-8. doi: 10.1016/j.jaut.2018.04.004. PMID: 29853344

  55. Raso F, Sagadiev S, Du S, Gage E, Arkatkar T, Metzler G, Stuart LM, Orr MT, Rawlings DJ, Jackson SW, Lacy-Hulbert A, Acharya M. αv Integrins regulate germinal center B cell responses through noncanonical autophagy. J Clin Invest. 2018 Aug 20. pii: 99597. doi: 10.1172/JCI99597. PMID: 29999501 | PMC6118577

  56. Reed MJ, Damodarasamy M, Pathan JL, Chan CK, Spiekerman C, Wight TN, Banks WA, Day AJ, Vernon RB, Keene CD. Increased Hyaluronan and TSG-6 in Association with Neuropathologic Changes of Alzheimer's Disease. J Alzheimers Dis. 2018 Nov 29. doi: 10.3233/JAD-180797. PMID: 30507579 | PMC6398602

  57. Reed MJ, Damodarasamy M, Pathan JL, Erickson MA, Banks WA, Vernon RB. The Effects of Normal Aging on Regional Accumulation of Hyaluronan and Chondroitin Sulfate Proteoglycans in the Mouse Brain. J Histochem Cytochem. 2018 May 1:22155418774779. doi: 10.1369/0022155418774779. PMID: 29782809

  58. Reeves SR, Barrow KA, Kolstad TK, White MP, Rich LM, Wight TN, Debley JS. Fibroblast gene expression following asthmatic bronchial epithelial cell conditioning correlates with epithelial donor lung function and exacerbation history. Sci Rep. 2018 Oct 25;8(1):15768. doi: 10.1038/s41598-018-34021-6. PMID: 30361541 | PMC6202408

  59. Reeves SR, Kang I, Chan CK, Barrow KA, Kolstad TK, White MP, Ziegler SF, Wight TN, Debley JS. Asthmatic bronchial epithelial cells promote the establishment of a Hyaluronan-enriched, leukocyte-adhesive extracellular matrix by lung fibroblasts. Respir Res. 2018 Aug 2;19(1):146. doi: 10.1186/s12931-018-0849-1. PMID: 30071849 | PMC6090698

  60. Renand A, Farrington M, Whalen E, Wambre E, Bajzik V, Chinthrajah S, Nadeau KC, Kwok WW. Heterogeneity of Ara h Component-Specific CD4 T Cell Responses in Peanut-Allergic Subjects. Front Immunol. 2018 Jun 25;9:1408. doi: 10.3389/fimmu.2018.01408. eCollection 2018. PMID: 29988522 | PMC6026622

  61. Renand A, Shamji MH, Harris KM, Qin T, Wambre E, Scadding GW, Wurtzen PA, Till SJ, Togias A, Nepom GT, Kwok WW, Durham SR. Synchronous immune alterations mirror clinical response during allergen immunotherapy. J Allergy Clin Immunol. 2018 May;141(5):1750-1760.e1. doi: 10.1016/j.jaci.2017.09.041. Epub 2017 Nov 9. PMID: 29128670 | PMC5938141

  62. Reynolds CJ, Suleyman OM, Ortega-Prieto AM, Skelton JK, Bonnesoeur P, Blohm A, Carregaro V, Silva JS, James EA, Maillère B, Dorner M, Boyton RJ, Altmann DM.  T cell immunity to Zika virus targets immunodominant epitopes that show cross-reactivity with other Flaviviruses. Sci Rep. 2018 Jan 12;8(1):672. doi: 10.1038/s41598-017-18781-1. PMID: 29330423 | PMC5766511

  63. Rims C, Uchtenhagen H, Kaplan MJ, Carmona-Rivera C, Carlucci P, Mikecz K, Markovics A, Carlin J, Buckner JH,James EA. Citrullinated Aggrecan Epitopes as Targets of Auto-reactive CD4+ T cells in Patients with Rheumatoid Arthritis. Arthritis Rheumatol. 2018 Nov 2. doi: 10.1002/art.40768. PMID: 30390384 | PMC6438725

  64. Santos AF, Couto-Francisco N, Bécares N, Kwok M, Bahnson HT, Lack G. A novel human mast cell activation test for peanut allergy. J Allergy Clin Immunol. 2018 May 3. pii: S0091-6749(18)30518-9. doi: 10.1016/j.jaci.2018.03.011. PMID: 29731128

  65. Singh MD, Ni M, Sullivan JM, Hamerman JA, Campbell DJ. B cell adaptor for PI3-kinase (BCAP) modulates CD8+ effector and memory T cell differentiation. J Exp Med. 2018 Aug 9. pii: jem.20171820. doi: 10.1084/jem.20171820. PMID: 30093532 | PMC6122975

  66. Smith JJ, Timoshevskaya N, Ye C, Holt C, Keinath MC, Parker HJ, Cook ME, Hess JE, Narum SR, Lamanna F, Kaessmann H, Timoshevskiy VA, Waterbury CKM, Saraceno C, Wiedemann LM, Robb SMC, Baker C, Eichler EE, Hockman D, Sauka-Spengler T, Yandell M, Krumlauf R, Elgar G, Amemiya CT. The sea lamprey germline genome provides insights into programmed genome rearrangement and vertebrate evolution. Nat Genet. 2018 Feb;50(2):270-277. doi: 10.1038/s41588-017-0036-1. Epub 2018 Jan 22. PMID: 29358652 | PMC5805609

  67. Snell LM, MacLeod BL, Law JC, Osokine I, Elsaesser HJ, Hezaveh K, Dickson RJ, Gavin MA, Guidos CJ, McGaha TL, Brooks DG. CD8(+) T Cell Priming in Established Chronic Viral Infection Preferentially Directs Differentiation of Memory-like Cells for Sustained Immunity. Immunity. 2018 Oct 1. pii: S1074-7613(18)30342-X. doi: 10.1016/j.immuni.2018.08.002. PMID: 30314757

  68. Sobel M, Kikuchi S, Chen L, Tang GL, Wight TN, Kenagy RD. Clinical factors that influence the cellular responses of saphenous veins used for arterial bypass. J Vasc Surg. 2018 Jun 15. pii: S0741-5214(18)31029-2. doi: 10.1016/j.jvs.2018.03.436. PMID: 29914830

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