2017 BRI Publications

The following list highlights BRI's 2017 publications. More selective listings of publications are also included on scientist biography pages. BRI scientists are listed in bold.

  1. Wang Y, Sosinowski T, Novikov A, Crawford F, Neau DB, Yang J, Kwok WW, Marrack P, Kappler JW, Dai S. C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes. Proc Natl Acad Sci U S A. 2017 Dec 18. pii: 201716527. doi: 10.1073/pnas.1716527115. PMID: 29255035

  2. Bogdani M, Blackman SM, Ridaura C, Bellocq JP, Powers AC, Aguilar-Bryan L. Structural abnormalities in islets from very young children with cystic fibrosis may contribute to cystic fibrosis-related diabetes. Sci Rep. 2017 Dec 8;7(1):17231. doi: 10.1038/s41598-017-17404-z. PMID: 29222447 | PMC5722914

  3. James EA, Abreu JRF, McGinty JW, Odegard JM, Fillié YE, Hocter CN, Culina S, Ladell K, Price DA, Alkanani A, Rihanek M, Fitzgerald-Miller L, Skowera A, Speake C, Gottlieb P, Davidson HW, Wong FS, Roep B, Mallone R; Immunology of Diabetes Society T Cell Workshop Committee. Combinatorial detection of autoreactive CD8(+) T cells with HLA-A2 multimers: a multi-centre study by the Immunology of Diabetes Society T Cell Workshop. Diabetologia. 2017 Dec 1. doi: 10.1007/s00125-017-4508-8. PMID: 29196783

  4. Nagy N, de la Zerda A, Kaber G, Johnson PY, Hu KH, Kratochvil MJ, Yadava K, Zhao W, Cui Y, Navarro G, Annes JP, Wight TN, Heilshorn SC, Bollyky PL, Butte MJ. Hyaluronan content governs tissue stiffness in pancreatic islet inflammation. J Biol Chem. 2017 Nov 28. pii: jbc.RA117.000148. doi: 10.1074/jbc.RA117.000148. PMID: 29183997
  5. Writing Committee for the Type 1 Diabetes TrialNet Oral Insulin Study Group, Krischer JP, Schatz DA, Bundy B, Skyler JS, Greenbaum CJ. Effect of Oral Insulin on Prevention of Diabetes in Relatives of Patients With Type 1 Diabetes: A Randomized Clinical Trial. JAMA. 2017 Nov 21;318(19):1891-1902. doi: 10.1001/jama.2017.17070. PMID: 29164254

  6. James EA. Direct Analysis of Insulin-Specific T Cells Provides New Insights. Diabetes. 2017 Dec;66(12):2940-2941. doi: 10.2337/dbi17-0041. PMID: 29162735

  7. Wambre E, Jeong D. Oral Tolerance Development and Maintenance. Immunol Allergy Clin North Am. 2018 Feb;38(1):27-37. doi: 10.1016/j.iac.2017.09.003. Epub 2017 Oct 26. PMID: 29132672

  8. Renand A, Shamji MH, Harris KM, Qin T, Wambre E, Scadding GW, Wurtzen PA, Till SJ, Togias A, Nepom GT, Kwok WW, Durham SR. Synchronous Immune Alterations Mirror Clinical Response During Allergen Immunotherapy. J Allergy Clin Immunol. 2017 Nov 8. pii: S0091-6749(17)31735-9. doi: 10.1016/j.jaci.2017.09.041. PMID: 29128670

  9. Altman MC, Reeves SR, Parker AR, Whalen E, Misura KM, Barrow KA, James RG, Hallstrand TS, Ziegler SF, Debley JS. Interferon response to respiratory syncytial virus by bronchial epithelium from children with asthma is inversely correlated with pulmonary function. J Allergy Clin Immunol. 2017 Oct 26. pii: S0091-6749(17)31645-7. doi: 10.1016/j.jaci.2017.10.004. PMID: 29106997

  10. Buckner JH, Greenbaum CJ. Stacking the Deck: Studies of Patients with Multiple Autoimmune Diseases Propelled Our Understanding of Type 1 Diabetes as an Autoimmune Disease. J Immunol. 2017 Nov 1;199(9):3011-3013. doi: 10.4049/jimmunol.1701299. PMID: 29061711

  11. Hao W, Wookwyk A, Beam C, Bahnson T, Palmer JP, Greenbaum CJ. Assessment of Beta Cell Mass and Function by AIRmax and IVGTT in High Risk Subjects for Type 1 Diabetes. J Clin Endocrinol Metab. 2017 Oct 12. doi: 10.1210/jc.2017-01713. PMID: 29040630

  12. Greenbaum C, Lord S, VanBuecken D. Emerging Concepts on Disease-Modifying Therapies in Type 1 Diabetes. Curr Diab Rep. 2017 Oct 17;17(11):119. doi:10.1007/s11892-017-0932-x. Review. PMID: 29039056

  13. Eken A, Duhen R, Singh AK, Fry M, Buckner JH, Kita M, Bettelli E, Oukka M. S1P1 deletion differentially affects TH17 and Regulatory T cells. Sci Rep. 2017 Oct 10;7(1):12905. doi: 10.1038/s41598-017-13376-2. PMID: 29018225 | PMC5635040

  14. Singh AK, Eken A, Hagin D, Komal K, Bhise G, Shaji A, Arkatkar T, Jackson SW, Bettelli E, Torgerson TR, Oukka M. DOCK8 regulates fitness and function of regulatory T cells through modulation of IL-2 signaling. JCI Insight. 2017 Oct 5;2(19). pii: 94275. doi: 10.1172/jci.insight.94275. PMID: 28978795

  15. Wu X, DeGottardi Q, Wu IC, Yu J, Wu L, Ye F, Kuo CT, Kwok WW, Chiu DT. Lanthanide-Coordinated Semiconducting Polymer Dots Used for Flow Cytometry and Mass Cytometry. Angew Chem Int Ed Engl. 2017 Sep 22. doi: 10.1002/anie.201708463. PMID: 28941061

  16. Sprouse ML, Blahnik G, Lee T, Tully N, Benarjee P, James EA, Redondo MJ, Bettini ML, Bettini M. Streamlined Single Cell TCR Isolation and Generation of Retroviral Vectors for In Vitro and In Vivo Expression of Human TCRs. J Vis Exp. 2017 Sep 10;(127). doi: 10.3791/55379. PMID: 28930975

  17. Kaya M, Mujtaba M, Ehrlich H, Salaberria AM, Baran T, Amemiya CT, Galli R, Akyuz L, Sargin I, Labidi J. On chemistry of γ-chitin. Carbohydr Polym. 2017 Nov 15;176:177-186. doi: 10.1016/j.carbpol.2017.08.076. Epub 2017 Aug 23. PMID: 28927596

  18. Chang MY, Kang I, Gale M Jr, Manicone AM, Kinsella MG, Braun KR, Wigmosta T, Parks WC, Altemeier WA, Wight TN, Frevert CW. Versican is Produced by Trif- and Type I Interferon-Dependent Signaling in Macrophages and Contributes to Fine-Control of Innate Immunity in Lungs. Am J Physiol Lung Cell Mol Physiol. 2017 Sep 14:ajplung.00353.2017. doi: 10.1152/ajplung.00353.2017. PMID: 28912382

  19. Arkatkar T, Du SW, Jacobs HM, Dam EM, Hou B, Buckner JH, Rawlings DJ, Jackson SW. B cell-derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity. J Exp Med. 2017 Sep 12. pii: jem.20170580. doi:10.1084/jem.20170580. PMID: 28899868 | PMC5679179

  20. Scholz EM, Marcilla M, Daura X, Arribas-Layton D, James EA, Alvarez I. Human Leukocyte Antigen (HLA)-DRB1*15:01 and HLA-DRB5*01:01 Present Complementary Peptide Repertoires. Front Immunol. 2017 Aug 21;8:984. doi: 10.3389/fimmu.2017.00984. eCollection 2017. PMID: 28871256 | PMC5566978

  21. Long SA, Thorpe J, Herold KC, Ehlers M, Sanda S, Lim N, Linsley PS, Nepom GT, Harris KM. Remodeling T cell compartments during anti-CD3 immunotherapy of type 1 diabetes. Cell Immunol. 2017 Sep;319:3-9. doi: 10.1016/j.cellimm.2017.07.007. Epub 2017 Aug 18. PMID: 28844471 | PMC5614459

  22. Metzler G, Dai X, Thouvenel CD, Khim S, Habib T, Buckner JH, Rawlings DJ. The Autoimmune Risk Variant PTPN22 C1858T Alters B Cell Tolerance at Discrete Checkpoints and Differentially Shapes the Naive Repertoire. J Immunol. 2017 Aug 11. pii: ji1700601. doi: 10.4049/jimmunol.1700601. PMID: 28801357

  23. Battaglia M, Anderson MS, Buckner JH, Geyer SM, Gottlieb PA, Kay TWH, Lernmark Å, Muller S, Pugliese A, Roep BO, Greenbaum CJ, Peakman M. Understanding and preventing type 1 diabetes through the unique working model of TrialNet. Diabetologia. 2017 Aug 2. doi: 10.1007/s00125-017-4384-2. Review. PMID: 28770323

  24. Wambre E, Bajzik V, DeLong JH, O'Brien K, Nguyen QA, Speake C, Gersuk VH, DeBerg HA, Whalen E, Ni C, Farrington M, Jeong D, Robinson D, Linsley PS, Vickery BP, Kwok WW. A phenotypically and functionally distinct human T(H)2 cell subpopulation is associated with allergic disorders. Sci Transl Med. 2017 Aug 2;9(401). pii: eaam9171. doi: 10.1126/scitranslmed.aam9171. PMID: 28768806

  25. Quinlan EM, King JJ, Amemiya CT, Hsu E, Larijani M. Biochemical regulatory features of AID remain conserved from lamprey to humans. Mol Cell Biol. 2017 Jul 17. pii: MCB.00077-17. doi: 10.1128/MCB.00077-17. PMID: 28716949 | PMC5615186

  26. Han H, Roan F, Ziegler SF. The atopic march: current insights into skin barrier dysfunction and epithelial cell-derived cytokines. Immunol Rev. 2017 Jul;278(1):116-130. doi: 10.1111/imr.12546. Review. PMID: 28658558 | PMC5492959

  27. Han H, Roan F, Johnston LK, Smith DE, Bryce PJ, Ziegler SF. IL-33 promotes gastrointestinal allergy in a TSLP-independent manner. Mucosal Immunol. 2017 Jun 28. doi: 10.1038/mi.2017.61. PMID: 28656964

  28. Carmona-Rivera C, Carlucci PM, Moore E, Lingampalli N, Uchtenhagen H, James E, Liu Y, Bicker KL, Wahamaa H, Hoffmann V, Catrina AI, Thompson P, Buckner JH, Robinson WH, Fox DA, Kaplan MJ. Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis. Sci Immunol. 2017 Apr;2(10). pii: eaag3358. doi: 10.1126/sciimmunol.aag3358. Epub 2017 Apr 14. PMID: 28649674 | PMC5479641

  29. Long AE, Tatum M, Mikacenic C, Buckner JH. A novel and rapid method to quantify Treg mediated suppression of CD4 T cells. J Immunol Methods. 2017 Jun 22. pii: S0022-1759(17)30185-0. doi: 10.1016/j.jim.2017.06.009. PMID: 28648384 | PMC5573621

  30. Kikuchi S, Chen L, Xiong K, Saito Y, Azuma N, Tang G, Sobel M, Wight TN, Kenagy RD. Smooth muscle cells of human veins show an increased response to injury at valve sites. J Vasc Surg. 2017 Jun 21. pii: S0741-5214(17)31132-1. doi:10.1016/j.jvs.2017.03.447. PMID: 28647196

  31. Boden EK, Lord JD. CD4 T Cells in IBD: Crossing the Line? Dig Dis Sci. 2017 Jun 23. doi: 10.1007/s10620-017-4655-2. PMID: 28646283

  32. Schwedhelm K, Thorpe J, Murray SA, Gavin M, Speake C, Greenbaum C, Cerosaletti K, Buckner J, Long SA. Attenuated IL-2R signaling in CD4 memory T cells of T1D subjects is intrinsic and dependent on activation state. Clin Immunol. 2017 Aug;181:67-74. doi: 10.1016/j.clim.2017.06.004. Epub 2017 Jun 20. PMID: 28645874 | PMC5564451

  33. Mpina M, Maurice NJ, Yajima M, Slichter CK, Miller HW, Dutta M, McElrath MJ, Stuart KD, De Rosa SC, McNevin JP, Linsley PS, Abdulla S, Tanner M, Hoffman SL, Gottardo R, Daubenberger CA, Prlic M. Controlled Human Malaria Infection Leads to Long-Lasting Changes in Innate and Innate-like Lymphocyte Populations. J Immunol. 2017 Jul 1;199(1):107-118. doi: 10.4049/jimmunol.1601989. Epub 2017 Jun 2. PMID: 28576979 | PMC5528886

  34. Lord JD, Shows DM. Thiopurine use associated with reduced B and natural killer cells in inflammatory bowel disease. World J Gastroenterol. 2017 May14;23(18):3240-3251. doi: 10.3748/wjg.v23.i18.3240. PMID: 28566883 | PMC5434429

  35. Cerosaletti K, Barahmand-Pour-Whitman F, Yang J, DeBerg HA, Dufort MJ, Murray SA, Israelsson E, Speake C, Gersuk VH, Eddy JA, Reijonen H, Greenbaum CJ, Kwok WW, Wambre E, Prlic M, Gottardo R, Nepom GT, Linsley PS. Single-Cell RNA Sequencing Reveals Expanded Clones of Islet Antigen-Reactive CD4(+) T Cells in Peripheral Blood of Subjects with Type 1 Diabetes. J Immunol. 2017 Jul 1;199(1):323-335. doi: 10.4049/jimmunol.1700172. Epub 2017 May 31. PMID: 28566371 | PMC5499675

  36. Gorman JA, Hundhausen C, Errett JS, Stone AE, Allenspach EJ, Ge Y, Arkatkar T, Clough C, Dai X, Khim S, Pestal K, Liggitt D, Cerosaletti K, Stetson DB, James RG, Oukka M, Concannon P, Gale M Jr, Buckner JH, Rawlings DJ. The A946T variant of the RNA sensor IFIH1 mediates an interferon program that limits viral infection but increases the risk for autoimmunity. Nat Immunol. 2017 Jul;18(7):744-752. doi: 10.1038/ni.3766. Epub 2017 May 29. PMID: 28553952 | PMC5697900

  37. Yang J, Wen X, Xu H, Torres-Chinn N, Speake C, Greenbaum CJ, Nepom GT, Kwok WW. Antigen-Specific T Cell Analysis Reveals That Active Immune Responses to β Cell Antigens Are Focused on a Unique Set of Epitopes. J Immunol. 2017 Jul 1;199(1):91-96. doi: 10.4049/jimmunol.1601570. Epub 2017 May 26. PMID: 28550202 | PMC5505653

  38. Stuart LM, Lacy-Hulbert A. GOP-1: Helping phagosomes pass the acid test. J Cell Biol. 2017 Jun 5;216(6):1517-1519. doi: 10.1083/jcb.201704047. Epub 2017 May 24. PMID: 28539387 | PMC5461036

  39. Bosi E, Boulware DC, Becker DJ, Buckner JH, Geyer S, Gottlieb PA, Henderson C, Kinderman A, Sosenko JM, Steck AK, Bingley PJ; Type 1 Diabetes TrialNet Study Group. Impact of Age and Antibody Type on Progression From Single to Multiple Autoantibodies in Type 1 Diabetes Relatives. J Clin Endocrinol Metab. 2017 Aug 1;102(8):2881-2886. doi: 10.1210/jc.2017-00569. PMID: 28531305 | PMC5546870

  40. Roan F, Ziegler SF. Human Group 1 Innate Lymphocytes Are Negative for Surface CD3ε but Express CD5. Immunity. 2017 May 16;46(5):758-759. doi:10.1016/j.immuni.2017.04.024. PMID: 28514677 | PMC5503209

  41. Eddy WE, Gong KQ, Bell B, Parks WC, Ziegler SF, Manicone AM. Stat5 Is Required for CD103(+) Dendritic Cell and Alveolar Macrophage Development and Protection from Lung Injury. J Immunol. 2017 Jun 15;198(12):4813-4822. doi:10.4049/jimmunol.1601777. Epub 2017 May 12. PMID: 28500076 | PMC5624516

  42. Karnell FG, Lin D, Motley S, Duhen T, Lim N, Campbell DJ, Turka LA, Maecker HT, Harris KM. Reconstitution of immune cell populations in multiple sclerosis patients after autologous stem cell transplantation. Clin Exp Immunol. 2017 Sep;189(3):268-278. doi: 10.1111/cei.12985. Epub 2017 Jun 7. Review. PMID: 28498568 | PMC5543487

  43. Han H, Ziegler SF. Intradermal administration of IL-33 induces allergic airway inflammation. Sci Rep. 2017 May 10;7(1):1706. doi: 10.1038/s41598-017-01863-5. PMID: 28490737 | PMC5431780

  44. Reed MJ, Vernon RB, Damodarasamy M, Chan CK, Wight TN, Bentov I, Banks WA. Microvasculature of the Mouse Cerebral Cortex Exhibits Increased Accumulation and Synthesis of Hyaluronan With Aging. J Gerontol A Biol Sci Med Sci. 2017 Jun 1;72(6):740-746. doi: 10.1093/gerona/glw213. PMID: 28482035

  45. Ramsey BW, Nepom GT, Lonial S. Academic, Foundation, and Industry Collaboration in Finding New Therapies. N Engl J Med. 2017 May 4;376(18):1762-1769. doi: 10.1056/NEJMra1612575. Review. PMID: 28467868

  46. Campbell DJ, Koch MA. Living in Peace: Host-Microbiota Mutualism in the Skin. Cell Host Microbe. 2017 Apr 12;21(4):419-420. doi: 10.1016/j.chom.2017.03.012. PMID: 28407479

  47. Courtade JA, Klimek-Abercrombie AM, Chen YC, Patel N, Lu PY, Speake C, Orban PC, Najafian B, Meneilly G, Greenbaum CJ, Warnock GL, Panagiotopoulos C, Verchere CB. Measurement of pro-islet amyloid polypeptide (1-48) in diabetes and islet transplants. J Clin Endocrinol Metab. 2017 Mar 24. doi: 10.1210/jc.2016-2773. PMID: 28368485

  48. Rust B, Wambre E. Human Immune Monitoring Techniques during Food Allergen Immunotherapy. Curr Allergy Asthma Rep. 2017 Apr;17(4):22. doi:10.1007/s11882-017-0689-y. Review. PMID: 28361386

  49. Archila LD, Khan FS, Bhatnagar N, Robinson D, Farrington ML, Kwok WW. αS1-Casein elucidate major T-cell responses in cow's milk allergy. J Allergy Clin Immunol. 2017 Mar 23. pii: S0091-6749(17)30427-X. doi: 10.1016/j.jaci.2017.02.028. PMID: 28343843 | PMC5591766

  50. Allenspach EJ, Finn LS, Rendi MH, Eken A, Singh AK, Oukka M, Taylor SD, Altman MC, Fligner CL, Ochs HD, Rawlings DJ, Torgerson TR. Absence of functional fetal regulatory T cells in humans causes in utero organ-specific autoimmunity. J Allergy Clin Immunol. 2017 Aug;140(2):616-619.e7. doi: 10.1016/j.jaci.2017.02.017. Epub 2017 Mar 16. PMID: 28322850

  51. Archila LL, Kwok WW. Tetramer-Guided Epitope Mapping: A Rapid Approach to Identify HLA-Restricted T-Cell Epitopes from Composite Allergens. Methods Mol Biol. 2017;1592:199-209. doi: 10.1007/978-1-4939-6925-8_16. PMID: 28315222

  52. Dasgupta A, Kjarsgaard M, Capaldi D, Radford K, Aleman F, Boylan C, Altman LC, Wight TN, Parraga G, O'Byrne PM, Nair P. A pilot randomised clinical trial of mepolizumab in COPD with eosinophilic bronchitis. Eur Respir J. 2017 Mar 15;49(3). pii: 1602486. doi: 10.1183/13993003.02486-2016. Print 2017 Mar. PMID: 28298405

  53. Symonová R, Havelka M, Amemiya CT, Howell WM, Kořínková T, Flajšhans M, Gela D, Ráb P. Molecular cytogenetic differentiation of paralogs of Hox paralogs in duplicated and re-diploidized genome of the North American paddlefish (Polyodon spathula). BMC Genet. 2017 Mar 2;18(1):19. doi: 10.1186/s12863-017-0484-8. PMID: 28253860 | PMC5335500

  54. Blazkova J, Gupta S, Liu Y, Gaudilliere B, Ganio EA, Bolen CR, Saar-Dover R, Fragiadakis GK, Angst MS, Hasni S, Aghaeepour N, Stevenson D, Baldwin N, Anguiano E, Chaussabel D, Altman MC, Kaplan MJ, Davis MM, Furman D. Multicenter Systems Analysis of Human Blood Reveals Immature Neutrophils in Males and During Pregnancy. J Immunol. 2017 Mar 15;198(6):2479-2488. doi:10.4049/jimmunol.1601855. Epub 2017 Feb 8. PMID: 28179497 | PMC5337813

  55. Acevedo-Calado M, James EA, Morran MP, Pietropaolo SL, Ouyang Q, Arribas-Layton D, Songini M, Liguori M, Casu A, Auchus RJ, Huang S, Yu L, Michels A, Gianani R, Pietropaolo M. Identification of Unique Antigenic Determinants in the Amino Terminus of IA-2 (ICA512) in Childhood and Adult Autoimmune Diabetes: New Biomarker Development. Diabetes Care. 2017 Apr;40(4):561-568. doi:10.2337/dc16-1527. Epub 2017 Feb 7. PMID: 28174261 | PMCID: PMC5360285

  56. Vandepas LE, Warren KJ, Amemiya CT, Browne WE. Establishing and maintaining primary cell cultures derived from the ctenophore Mnemiopsis leidyi. J Exp Biol. 2017 Apr 1;220(Pt 7):1197-1201. doi: 10.1242/jeb.152371. Epub 2017 Jan 30. PMID: 28137975

  57. Kashiwagi M, Hosoi J, Lai JF, Brissette J, Ziegler SF, Morgan BA, Georgopoulos K. Direct control of regulatory T cells by keratinocytes. Nat Immunol. 2017 Mar;18(3):334-343. doi: 10.1038/ni.3661. Epub 2017 Jan 16. PMID: 28092372 | PMC5310986

  58. Duggan JM, Buechler MB, Olson RM, Hohl TM, Hamerman JA. BCAP inhibits proliferation and differentiation of myeloid progenitors in the steady state and during demand situations. Blood. 2017 Mar 16;129(11):1503-1513. doi:10.1182/blood-2016-06-719823. Epub 2017 Jan 13. PMID: 28087538 | PMC5356451

  59. Azzi J, Thueson L, Moore R, Abdoli R, Reijonen H, Abdi R. PI3Kγ Deficient NOD-Mice Are Protected from Diabetes by Restoring the Balance of Regulatory to Effector-T-Cells. PLoS One. 2017 Jan 12;12(1):e0169695. doi: 10.1371/journal.pone.0169695. eCollection 2017. PMID: 28081180 | PMC5231340

  60. Wight TN, Frevert CW, Debley JS, Reeves SR, Parks WC, Ziegler SF. Interplay of extracellular matrix and leukocytes in lung inflammation. Cell Immunol. 2017 Feb;312:1-14. doi: 10.1016/j.cellimm.2016.12.003. Epub 2016 Dec 23. Review. PMID: 28077237 | PMC5290208

  61. Eslami Rasekh M, Chiatante G, Miroballo M, Tang J, Ventura M, Amemiya CT, Eichler EE, Antonacci F, Alkan C. Discovery of large genomic inversions using long range information. BMC Genomics. 2017 Jan 10;18(1):65. doi: 10.1186/s12864-016-3444-1. PMID: 28073353 | PMC5223412.

  62. Jourde-Chiche N, Whalen E, Gondouin B, Speake C, Gersuk V, Dussol B, Burtey S, Pascual V, Chaussabel D, Chiche L. Modular transcriptional repertoire analyses identify a blood neutrophil signature as a candidate biomarker for lupus nephritis. Rheumatology (Oxford). 2017 Mar 1;56(3):477-487. doi: 10.1093/rheumatology/kew439. PMID: 28031441

  63. Speake C, Whalen E, Gersuk VH, Chaussabel D, Odegard JM, Greenbaum CJ. Longitudinal monitoring of gene expression in ultra-low-volume blood samples self-collected at home. Clin Exp Immunol. 2017 May;188(2):226-233. doi:10.1111/cei.12916. Epub 2017 Mar 2. PMID: 28009047 | PMC5383441

  64. Gaucherand L, Falk BA, Evanko SP, Workman G, Chan CK, Wight TN. Crosstalk Between T Lymphocytes and Lung Fibroblasts: Generation of a Hyaluronan-Enriched Extracellular Matrix Adhesive for Monocytes. J Cell Biochem. 2017 Aug;118(8):2118-2130. doi: 10.1002/jcb.25842. Epub 2017 Apr 18. PMID: 27982477 | PMC5538566

  65. Wight TN. Provisional matrix: A role for versican and hyaluronan. Matrix Biol. 2017 Jul;60-61:38-56. doi: 10.1016/j.matbio.2016.12.001. Epub 2016 Dec 6. Review. PMID: 27932299 | PMC5438907

  66. Joo S, Fukuyama Y, Park EJ, Yuki Y, Kurashima Y, Ouchida R, Ziegler SF, Kiyono H. Critical role of TSLP-responsive mucosal dendritic cells in the induction of nasal antigen-specific IgA response. Mucosal Immunol. 2017 Jul;10(4):901-911. doi: 10.1038/mi.2016.103. Epub 2016 Dec 7. PMID: 27924821

  67. Michels AW, Landry LG, McDaniel KA, Yu L, Campbell-Thompson M, Kwok WW, Jones KL, Gottlieb PA, Kappler JW, Tang Q, Roep BO, Atkinson MA, Mathews CE, Nakayama M. Islet-Derived CD4 T Cells Targeting Proinsulin in Human Autoimmune Diabetes. Diabetes. 2017 Mar;66(3):722-734. doi: 10.2337/db16-1025. Epub 2016 Dec 5. PubMed PMID: 27920090 | PMC5319719

  68. Balaji S, Wang X, King A, Le LD, Bhattacharya SS, Moles CM, Butte MJ, de Jesus Perez VA, Liechty KW, Wight TN, Crombleholme TM, Bollyky PL, Keswani SG. Interleukin-10-mediated regenerative postnatal tissue repair is dependent on regulation of hyaluronan metabolism via fibroblast-specific STAT3 signaling. FASEB J. 2017 Mar;31(3):868-881. doi: 10.1096/fj.201600856R. Epub 2016 Nov 30. PMID: 27903619 | PMC5295728

  69. Kang I, Harten IA, Chang MY, Braun KR, Sheih A, Nivison MP, Johnson PY, Workman G, Kaber G, Evanko SP, Chan CK, Merrilees MJ, Ziegler SF, Kinsella MG, Frevert CW, Wight TN. Versican Deficiency Significantly Reduces Lung Inflammatory Response Induced by Polyinosine-Polycytidylic Acid Stimulation. J Biol Chem. 2017 Jan 6;292(1):51-63. doi: 10.1074/jbc.M116.753186. Epub 2016 Nov 28. PMID: 27895126 | PMC5217699

  70. Lima SQ, Costa CM, Amemiya CT, Schneider I. Morphological And Molecular Analyses of an Anatomical Novelty: The Pelvic Fin Filaments of the South American Lungfish. J Exp Zool B Mol Dev Evol. 2017 Jan;328(1-2):97-105. doi: 10.1002/jez.b.22711. Epub 2016 Nov 9. PMID: 27862964

  71. Bonifacio E, Mathieu C, Nepom GT, Ziegler AG, Anhalt H, Haller MJ, Harrison LC, Hebrok M, Kushner JA, Norris JM, Peakman M, Powers AC, Todd JA, Atkinson MA. Rebranding asymptomatic type 1 diabetes: the case for autoimmune beta cell disorder as a pathological and diagnostic entity. Diabetologia. 2017 Jan;60(1):35-38. Epub 2016 Oct 26. PMID: 27785529 | PMC5516264

  72. Sheih A, Parks WC, Ziegler SF. GM-CSF produced by the airway epithelium is required for sensitization to cockroach allergen. Mucosal Immunol. 2017 May;10(3):705-715. doi: 10.1038/mi.2016.90. Epub 2016 Oct 12. PMID: 27731325 | PMC5389932

  73. Gebe JA, Yadava K, Ruppert SM, Marshall P, Hill P, Falk BA, Sweere JM, Han H, Kaber G, Medina C, Mikecz K, Ziegler SF, Balaji S, Keswani SG, Perez VA, Butte MJ, Nadeau K, Altemeier WA, Fanger N, Bollyky PL. Modified High-Molecular-Weight Hyaluronan Promotes Allergen-Specific Immune Tolerance. Am J Respir Cell Mol Biol. 2017 Jan;56(1):109-120. doi: 10.1165/rcmb.2016-0111OC. PMID: 27598620 | PMC5248962

  74. Gan RW, Demoruelle MK, Deane KD, Weisman MH, Buckner JH, Gregersen PK, Mikuls TR, O'Dell JR, Keating RM, Fingerlin TE, Zerbe GO, Clare-Salzler MJ, Holers VM, Norris JM. Omega-3 fatty acids are associated with a lower prevalence of autoantibodies in shared epitope-positive subjects at risk for rheumatoid arthritis. Ann Rheum Dis. 2017 Jan;76(1):147-152. doi:10.1136/annrheumdis-2016-209154. Epub 2016 May 17. PMID: 27190099 | PMC5371398

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