Publications

The following list highlights BRI's 2020 publications. More selective listings of publications are also included on scientist biography pages. BRI Principal Investigators are listed in bold.

  1. Berkson JD, Slichter CK, DeBerg HA, Delaney MA, Woodward-Davis AS, Maurice NJ, Lwo Y, Ko A, Hsu J, Chiu YW, Linsley PS, Dixon D, Prlic M. Inflammatory Cytokines Induce Sustained CTLA-4 Cell Surface Expression on Human MAIT Cells. Immunohorizons. 2020 Jan 23;4(1):14-22. doi: 10.4049/immunohorizons.1900061. PMID: 31974109

  2. Bogdani M, Speake C, Dufort MJ, Johnson PY, Larmore MJ, Day AJ, Wight TN, Lernmark Å, Greenbaum CJ. Hyaluronan deposition in islets may precede and direct the location of islet immune-cell infiltrates. Diabetologia. 2020 Jan 6. doi: 10.1007/s00125-019-05066-7. PMID: 31907557 | PMC7002022

  3. Harten IA, Kaber G, Agarwal KJ, Kang I, Ibarrientos SR, Workman G, Chan CK, Nivison MP, Nagy N, Braun KR, Kinsella MG, Merrilees MJ, Wight TN. The Synthesis and Secretion of Versican Isoform V3 by Mammalian Cells: A Role for N-linked Glycosylation. Matrix Biol. 2020 Jan 27. pii: S0945-053X(20)30008-1. doi: 10.1016/j.matbio.2020.01.002. PMID: 32001344

  4. Li D, Matta B, Song S, Nelson V, Diggins K, Simpfendorfer KR, Gregersen PK, Linsley P, Barnes BJ. IRF5 genetic risk variants drive myeloid-specific IRF5 hyperactivation and presymptomatic SLE. JCI Insight. 2020 Jan 30;5(2). pii: 124020. doi: 10.1172/jci.insight.124020. PMID: 31877114

  5. Reeves SR, Barrow KA, Rich LM, White MP, Shubin NJ, Chan CK, Kang I, Ziegler SF, Piliponsky AM, Wight TN, Debley JS. Respiratory Syncytial Virus Infection of Human Lung Fibroblasts Induces a Hyaluronan-Enriched Extracellular Matrix That Binds Mast Cells and Enhances Expression of Mast Cell Proteases. Front Immunol. 2020 Jan 28;10:3159. doi: 10.3389/fimmu.2019.03159. PMID: 32047499 | PMC6997473

  6. Sheih A, Voillet V, Hanafi LA, DeBerg HA, Yajima M, Hawkins R, Gersuk V, Riddell SR, Maloney DG, Wohlfahrt ME, Pande D, Enstrom MR, Kiem HP, Adair JE, Gottardo R, Linsley PS, Turtle CJ. Clonal kinetics and single-cell transcriptional profiling of CAR-T cells in patients undergoing CD19 CAR-T immunotherapy. Nat Commun. 2020 Jan 10;11(1):219. doi: 10.1038/s41467-019-13880-1. PMID: 31924795 | PMC6954177

  7. Speake C, Ylescupidez A, Neiman D, Shemer R, Glaser B, Tersey SA, Usmani-Brown S, Clark P, Wilhelm JJ, Bellin MD, Herold KC, Mirmira RG, Dor Y, Evans-Molina C. Circulating unmethylated insulin DNA as a biomarker of human beta cell death: a multi-laboratory assay comparison. J Clin Endocrinol Metab. 2020 Jan 8. pii: dgaa008. doi: 10.1210/clinem/dgaa008. PMID: 31913467 | PMC7015459

  8. Wiedeman AE, Muir VS, Rosasco MG, DeBerg HA, Presnell S, Haas B, Dufort MJ, Speake C, Greenbaum CJ, Serti E, Nepom GT, Blahnik G, Kus AM, James EA, Linsley PS, Long SA. Autoreactive CD8+ T cell exhaustion distinguishes subjects with slow type 1 diabetes progression. J Clin Invest. 2020 Jan 2;130(1):480-490. doi: 10.1172/JCI126595. PMID: 31815738 | PMC6934185

  9. Bolouri H, Young M, Beilke J, Johnson R, Fox B, Huang L, Santini CC, Hill CM, Vries AVV, Shannon PT, Dervan A, Sivakumar P, Trotter M, Bassett D, Ratushny A. Integrative network modeling reveals mechanisms underlying T cell exhaustion. Sci Rep. 2020 Feb 5;10(1):1915. doi: 10.1038/s41598-020-58600-8. PMID: 32024856 | PMC7002445

  10. Kabata H, Flamar AL, Mahlakõiv T, Moriyama S, Rodewald HR, Ziegler SF, Artis D. Targeted deletion of the TSLP receptor reveals cellular mechanisms that promote type 2 airway inflammation. Mucosal Immunol. 2020 Feb 17. doi: 10.1038/s41385-020-0266-x. PMID: 32066836

  11. Perkin MR, Bahnson HT, Lack G; EAT Study Team. Reply. J Allergy Clin Immunol. 2020 Feb 25. pii: S0091-6749(20)30103-2. doi: 10.1016/j.jaci.2020.01.015. PMID: 32111420

  12. Shubin NJ, Clauson M, Niino K, Kasprzak V, Tsuha A, Guga E, Bhise G, Acharya M, Snyder JM, Debley JS, Ziegler SF, Piliponsky AM. Thymic stromal lymphopoietin protects in a model of airway damage and inflammation via regulation of caspase-1 activity and apoptosis inhibition. Mucosal Immunol. 2020 Feb 26. doi: 10.1038/s41385-020-0271-0. PMID: 32103153

  13. So M, O'Rourke C, Bahnson HT, Greenbaum CJ, Speake C. Autoantibody Reversion: Changing Risk Categories in Multiple-Autoantibody-Positive Individuals. Diabetes Care. 2020 Feb 4. pii: dc191731. doi: 10.2337/dc19-1731. PMID: 32019856

  14. Wen X, Yang J, James E, Chow IT, Reijonen H, Kwok WW. Increased islet antigen-specific regulatory and effector CD4+ T cells in healthy individuals with the type 1 diabetes-protective haplotype. Sci Immunol. 2020 Feb 14;5(44). pii: eaax8767. doi: 10.1126/sciimmunol.aax8767. PMID: 32060144