Our goal is to combine expansion microscopy (ExMicro) and our virtual reality imaging tool (ConfocalVR), to reveal details of host-pathogen interactions that are otherwise not accessible. With the combined technology we are able to enlarge, explore and analyze cell structures far beyond the capabilities of traditional light microscopy. By creating an immersive visualization environment, we will be able to investigate complex high dimensional host-pathogen interactions.

Expanding tissue to see the invisible

Through virtual reality (VR) technology developed specifically for this purpose, we are able to see and manipulate the original stack of 2D expansion microscopy images in 3D, achieving a 360 degree view of tissue organizations and interactions.

The system to convert expansion microscopy data into VR 3D images will be affordable and easily accessible to researchers and physicians in developing countries. It will also enable four or more people to collaborate remotely, to view, manipulate, and discuss ExMicro images.

An essential tool for visualization

Through virtual reality (VR) technology developed specifically for this purpose, we are able to see and manipulate the original stack of 2D expansion microscopy images in full 3D, achieving an immersive view of tissue organization and protein interactions.

The system to convert expansion microscopy data into VR 3D images is affordable and easily accessible to researchers and physicians in developing countries. It will also enable four or more researchers to collaborate with each other from remote sites, to view, manipulate, discuss, and understand nano-resolution ExMicro images.

ExMicro VR: Visualizing details of the immune system

The ability to work with multiplex nanoscopy images in an immersive visual environment will allow scientists to understand details of host-pathogen interactions that have been unexplored thus far. More broadly, giving access to this high-resolution microscopy and visualization technology will accelerate scientists’ understanding of complex protein interactions and provide insight into disease processes faster. This website will enable any wet-lab to perform multiplexed high-resolution microscopy with image interpretation in VR using already familiar microscopes and reagents.

Our Team

• Benaroya Research Institute at Virginia Mason: Caroline Stefani, PhD, Adam Lacy-Hulbert, PhD
• Carnegie Mellon University College of Science: Yongxin (Leon) Zhao, PhD
• Immersive Science LLC: Thomas Skillman, CEO