Infectious Diseases & Vaccines Biorepository

Principal Investigator

Uma Malhotra, MD
Infectious Diseases
Virginia Mason Medical Center
Benaroya Research Institute

What is the Infectious Diseases & Vaccines Biorepository?

The Infectious Diseases and Vaccines Registry and Biorepository is a confidential list of people who are willing to participate in a vaccine study, have had a virus or who have lived in a Dengue virus risk area.

Study volunteers are willing to receive a vaccine or donate a blood sample and provide health information to support scientific research that will help improve our understanding of the immune response to viruses and bacterial infections that are a major threat to populations worldwide. Donated samples and personal and family health information is used by scientists in the laboratory and in analysis to help us better understand the causes and long term health effects of infectious and bacterial diseases and how vaccination prevents infection. All of the information gathered is kept confidential, and samples and health information used by scientists are coded with a number, not your name.

What are BRI scientists studying?

Researchers are working to better understand the nature of the human immune response to bacterial, fungal and viral infections, which are the leading causes of mortality and morbidity worldwide. Infections threatening world populations are expanding geographically with a changing epidemiology, as exemplified by the emergence of West Nile Virus in the Americas and Japanese Encephalitis Virus in Australasia.

Currently there are no highly effective vaccines for the prevention of many of infections that threaten the world's population. Infectious disease and vaccine research at BRI focuses on, but is not limited to, the study of influenza, Dengue, Yellow Fever, Japanese Encephalitis, West Nile, aspergillosis and may other infectious diseases. Our goal is to advance diagnostic and therapeutic interventions, which may lead to improved overall health conditions worldwide.

To learn more about this subject, please visit the Infectious Diseases information page.

Who can participate?

We are currently looking for adults, age 18 and older, who do not have a history of immune-mediated disease and who:

  • Had or currently have a viral infection

  • Are planning on getting a vaccine or have already received one

  • Have lived in a Dengue virus risk area for 10 or more years, such as in India, Indonesia, Vietnam, Thailand, Philippines, Sri Lanka, Singapore or other Dengue risk areas

  • Have received or will receive a vaccine to prevent a virus

Vaccine Studies

  • Yellow Fever Virus Vaccinees
  • Japanese Encephalitis Virus Vaccinees
  • Influenza (flu) Vaccinees
  • H1N1 Vaccinees
  • Seasonal & H1N1 Combination Vaccinees

Virus Positive Studies

  • West Nile Virus
  • Dengue Virus
  • Influenza A

Other Infection Studies

  • Rhinovirus
  • Aspergillosis
  • Clostridium Difficile
  • Others

We are also looking for friends and family members of all ages who do not have an immune-mediated or autoimmune disease, to join our Healthy Volunteer Registry.

To learn more about this opportunity to participate, please visit the Healthy Volunteer Registry & Biorepository.

How can I help?

You can help by encouraging friends and family members without autoimmune or immune mediated disease to donate to our Healthy Volunteer Registry & Biorepository.