Daniel J. Campbell, PhD
Dr. Campbell graduated with honors from the University of Michigan in 1993, and received his PhD in Molecular and Cell Biology from the University of California, Berkeley in 1998. Following a postdoctoral fellowship at Stanford University, Dr. Campbell joined the faculty of the Benaroya Research Institute as an Assistant Member in 2003. He is also an Affiliate Assistant Professor in the Department of Immunology at the University of Washington School of Medicine.
Areas of Research
Research in Dr. Campbell’s laboratory is focused on understanding the regulatory mechanisms that modulate immune responses during autoimmunity and infection. In particular, we are studying how a population of leukocytes called regulatory T cells functions to restrain immune responses, and how these cells can have beneficial effects in preventing autoimmunity, but also can promote chronic infection with pathogens such as Mycobacterium tuberculosis.
Meghan A. Koch, G. Tucker-Heard, N. R. Perdue, J. R. Killebrew, Kevin B. Urdahl, Daniel J. Campbell. (2008). T-bet controls regulatory T cell migration and expansion during type-1 inflammatory responses. Submitted
Jan C. Dudda, N. Perdue, E. Bachtanian and Daniel J. Campbell. (2008). Foxp3+ regulatory T cells maintain immune homeostasis in the skin. Submitted.
Sather BD, Treuting P, Perdue N, Miazgowicz M, Fontenot JD, Rudensky AY, Campbell DJ (Jun 2007) Altering the distribution of Foxp3(+) regulatory T cells results in tissue-specific inflammatory disease., Journal of Experimental Medicine, 204 (6), 1335-47.
Campbell DJ, Ziegler SF (Apr 2007) FOXP3 modifies the phenotypic and functional properties of regulatory T cells., Nature Reviews of Immunology, 7 (4), 305-10.
Humblet-Baron S, Sather B, Anover S, Becker-Herman S, Kasprowicz DJ, Khim S, Nguyen T, Hudkins-Loya K, Alpers CE, Ziegler SF, Ochs H, Torgerson T, Campbell DJ, Rawlings DJ (Feb 2007) Wiskott-Aldrich syndrome protein is required for regulatory T cell homeostasis., Journal of Clinical Investigation, 117 (2), 407-18.
Arnold CN, Campbell DJ, Lipp M, Butcher EC (Jan 2007) The germinal center response is impaired in the absence of T cell-expressed CXCR5., Eur J Immunol, 37 (1), 100-9.