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Scientific Papers

Current list of BRI Publications
2012 Publications 

  1. Tattermusch S, Skinner JA, Chaussabel D, Banchereau J, Berry MP, McNab FW, O'Garra A, Taylor GP, and Bangham CR. Systems Biology Approaches Reveal a Specific Interferon-Inducible Signature in HTLV-1 Associated Myelopathy PLoS. Pathog. 8:e1002480, 2012

  2. Chang MY, Chan CK, Braun KR, Green PS, O'Brien KD, Chait A, Day AJ, and Wight TN. Monocyte to macrophage differentiation: Synthesis and secretion of a complex extracellular matrix J. Biol. Chem. 2012

  3. Schulze Zur, Wiesch J, Ciuffreda D, Lewis-Ximenez L, Kasprowicz V, Nolan BE, Streeck H, Aneja J, Reyor LL, Allen TM, Lohse AW, McGovern B, Chung RT, Kwok WW, Kim AY, and Lauer GM. Broadly directed virus-specific CD4+ T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence J. Exp. Med. 209:61-75, 2012

  4. Crawford DHG, Fletcher LM, Kowdley KV. “Iron and Liver Disease” Iron Physiology and Pathophysiology in Humans. GJ Anderson, GD McLaren (Eds). New York: Springer Science+Media, LLC, pp. 441-454. Book Chapter, 2012

  5. Deakin JE, Bender HS, Pearse A-M, Rens W, O'Brien PCM, Ferguson-Smith MA, Cheng Y, Morris K, Taylor R, Stuart A, Belov K, Amemiya CT, Murchison EP, Papenfuss AT, Graves JM. Genomic Restructuring in the Tasmanian Devil Facial Tumour: Chromosome Painting and Gene Mapping Provide Clues to Evolution of a Transmissible Tumour. PLoS Genet 8(2): e1002483. doi:10.1371/journal.pgen.1002483, 2012

  6. Kwok WW, Tan V, Gillette L, Littell CT, Soltis MA, LaFond RB, Yang J, James EA, and Delong JH. Frequency of Epitope-Specific Naive CD4+ T Cells Correlates with Immunodominance in the Human Memory Repertoire J. Immunol. 2012

  7. Habib T, Funk A, Rieck M, Brahmandam A, Dai X, Panigrahi A, Prak E, Meyer-Bahlmburg A, Sanda S, Greenbaum C, Rawlings D, Buckner JH. Altered B cell homeostasis is associated with Type I diabetes and carriers of the PTPN22 allelic variant, J Immunol. Jan 1;188(1):487-96. In This Issue section of J Immunol., 2012

  8. Hondowicz BD, Schwedhelm KV, Kas A, Tasch MA, Rawlings C, Ramchurren N, McIntosh M, D’Amico LA, Sanda S, Standifer NE, Shendure J, Stone B. Discovery of T cell antigens by high-throughput screening of synthetic minigene libraries. PLoS One. 7:e29949, 2012

  9. Iseki M, Omori-Miyake M, Xu W, Sun X, Takaki S, Rawlings DJ, and Ziegler SF. Thymic stromal lymphopoietin (TSLP)-induced polyclonal B-cell activation and autoimmunity are mediated by CD4+ T cells and IL-4 Int. Immunol. 2012

  10. Kanter JE, Kramer F, Barnhart S, Averill MM, Vivekanandan-Giri A, Vickery T, Li LO, Becker L, Yuan W, Chait A, Braun KR, Potter-Perigo S, Sanda S, Wight TN, Pennathur S, Serhan CN, Heinecke JW, Coleman RA, and Bornfeldt KE. Diabetes promotes an inflammatory macrophage phenotype and atherosclerosis through acyl-CoA synthetase 1 Proc. Natl. Acad. Sci. U. S. A., 2012

  11. Kean TJ, Duesler L, Young RG, Dadabayev A, Olenyik A, Penn M, Wagner J, Fink DJ, Caplan AI, Dennis JE.  Development of a peptide-targeted, myocardial ischemia-homing, mesenchymal stem cell.  J Drug Target.  20:23-32, 2012

  12. Maliken BD, Avrin WF, Nelson JE, Mooney J, Kumar S, Kowdley KV. Room-temperature susceptometry predicts biopsy-determined hepatic iron in patients with elevated serum ferritin. Ann Hepatol. Jan;11(1):77-84, 2012

  13. Ni M, MacFarlane AW, Toft M, Lowell CA, Campbell KS, and Hamerman JA. B-cell adaptor for PI3K (BCAP) negatively regulates Toll-like receptor signaling through activation of PI3K Proc. Natl. Acad. Sci. U. S. A 109:267-272, 2012

  14. Mounts T, Ginley N, Schluchter M, Dennis JE.  Optimization of the expansion and differentiation of rabbit chondrocytes in vitro.  Cartilage.  Online first, Feb 14, 2012

  15. Nishiura H, Kido M, Aoki N, Iwamoto S, Maruoka R, Ikeda A, Chiba T, Ziegler SF, and Watanabe N. Increased susceptibility to autoimmune gastritis in thymic stromal lymphopoietin receptor-deficient mice J. Immunol. 188:190-197, 2012

  16. Chow IT, James EA, Tan V, Moustakas AK, Papadopoulos GK, and Kwok WW. DRB1*12:01 presents a unique subset of epitopes by preferring aromatics in pocket 9 Mol. Immunol. 2012

  17. Oling V, Reijonen H, Simell O, Knip M, and Ilonen J. Autoantigen-specific memory CD4(+) T cells are prevalent early in progression to Type 1 diabetes Cell Immunol. 2012

  18. Omori-Miyake M and Ziegler SF. Mouse Models of Allergic Diseases: TSLP and Its Functional Roles Allergol. Int. 2012

  19. Robins H, Desmarais C, Matthis J, Livingston R, Andriesen J, Reijonen H, Carlson C, Nepom GT, Yee C, and Cerosaletti K. Ultra-sensitive detection of rare T cell clones J. Immunol. Methods 375:14-19, 2012

  20. Reed MJ and Vernon RB. Miniaturized assays of angiogenesis in vitro Methods Mol. Biol. 843:87-98, 2012

  21. Schubert DA, Gordo S, Sabatino JJ Jr., Vardhana S, Gagnon E, Sethi DK, Seth NP, Choudhuri K, Reijonen H, Nepom GT, Evavold BD, Dustin ML, and Wucherpfennig KW. Self-reactive human CD4 T cell clones form unusual immunological synapses J. Exp. Med. 209:335-352, 2012

  22. Vos MB, Colvin R, Belt P, Molleston JP, Murray KF, Rosenthal P, Schwimmer JB, Tonascia J, Unalp A, Lavine JE; NASH CRN Research Group [Kowdley KV]. Correlation of vitamin E, uric acid, and diet composition with histologic features of pediatric NAFLD. J Pediatr Gastroenterol Nutr. 2012 Jan;54(1):90-6, 2012

2011 Publications

  1. ALSUntangled Group (including Ravits J). ALSUntangled No. 8: Low dose naltrexone for ALS. Amyotroph Lateral Scler. 12(1):76-8. Epub 2010 Dec 21. January 2011

  2. ALSUntangled Group (including Ravits J). ALSUntangled No. 9: Blue-green algae (Spirulina) as a treatment for ALS. Amyotroph Lateral Scler.12(2):153-5. March 2011

  3. Angheloiu GO, Haka AS, Georgakoudi I, Arendt J, Muller MG, Scepanovic OR, Evanko SP, Wight TN, Mukherjee P, Waldeck DH, Dasari RR, Fitzmaurice M, Kramer JR, and Feld MS. Detection of coronary atherosclerotic plaques with superficial proteoglycans and foam cells using real-time intrinsic fluorescence spectroscopy Atherosclerosis 215:96-102, 2011

  4. Averill MM, Barnhart S, Becker L, Li X, Heinecke JW, Leboeuf RC, Hamerman JA, Sorg C, Kerkhoff C, and Bornfeldt KE. S100A9 differentially modifies phenotypic states of neutrophils, macrophages, and dendritic cells: implications for atherosclerosis and adipose tissue inflammation Circulation 123:1216-1226, 2011

  5. Bacon BR, Adams PC, Kowdley KV, Powell LW, and Tavill AS. Diagnosis and management of hemochromatosis: 2011 practice guidelines by the American association for the study of liver diseases Hepatology 2011

  6. Bauer J, Liu RW, Kean TJ, Dennis JE, Petersilge W, Gilmore A.  A comparison of five treatment protocols for contaminated bone grafts in reference to sterility and cell viability.  J Bone Joint Surg Am. 93(5):439-44. 2011

  7. Bollyky PL, Wu RP, Falk BA, Lord JD, Long SA, Preisinger A, Teng B, Holt GE, Standifer NE, Braun KR, Xie CF, Samuels PL, Vernon RB, Gebe JA, Wight TN, and Nepom GT. ECM components guide IL-10 producing regulatory T-cell (TR1) induction from effector memory T-cell precursors Proc. Natl. Acad. Sci. U. S. A 2011

  8. Bonvalet M, Wambre E, Moussu H, Horiot S, Kwok WW, Louise A, Ebo D, Hoarau C, Van Overtvelt L, Baron-Bodo V, and Moingeon P. Comparison between major histocompatibility complex class II tetramer staining and surface expression of activation markers for the detection of allergen-specific CD4(+) T cells Clin. Exp. Allergy 2011

  9. Boyer TD, Sanyal AJ, Garcia-Tsao G, Blei A, Carl D, Bexon AS, Teuber P; Terlipressin Study Group [Kowdley KV]. Predictors of response to terlipressin plus albumin in hepatorenal syndrome (HRS) type 1: relationship of serum creatinine to hemodynamics. J Hepatol. 2011 Aug;55(2):315-21.

  10. Brooks-Worrell B, Tree T, Mannering SI, Durinovic-Belló I, James EA, Gottlieb P, Wong FS, Zhou Z, Yang L, Cilio CM, Reichow J, Menart B, Rutter R, Schreiner R, Pham M, Petrich de Marquesini L, Thorpe J, Lou O, Scotto M, Mallone R, Schloot NC. Comparison of cryopreservation methods on T-cell responses to islet and control antigens from type 1diabetic patients and controls. T-Cell Workshop Committee, Immunology of Diabetes Society. Diabetes Metab Res Rev 2011; 27: Eupub, DOI: 10.1002/dmrr.1245

  11. Brunt EM, Kleiner DE, Wilson LA, Belt P, Neuschwander-Tetri BA for the NASH Clinical Research Network (CRN) [Kowdley KV]:  Nonalcoholic Fatty Liver Disease (NAFLD) Activity Score and the histopathologic diagnosis in NAFLD:  Distinct clinicopathologic meanings.  Hepatology, 53: 810-820. 2011

  12. Burke III GW, Vendrame F, Pileggi A, Ciancio G, Reijonen H, and Pugliese A. Recurrence of autoimmunity following pancreas transplantation Curr. Diab. Rep. 11:413-419, 2011

  13. Campbell DJ and Koch MA. Phenotypical and functional specialization of FOXP3(+) regulatory T cells Nat. Rev. Immunol. 11:119-130, 2011

  14. Campbell DJ and Koch MA. T(reg) cells: patrolling a dangerous neighborhood Nat. Med. 17:929-930, 2011

  15. Campbell DJ. Regulatory T cells GATA have it Immunity. 35:313-315, 2011

  16. Chiba T, Chang MY, Wang S, Wight TN, McMillen TS, Oram JF, Vaisar T, Heinecke JW, De Beer FC, De Beer MC, and Chait A. Serum Amyloid A Facilitates the Binding of High-Density Lipoprotein From Mice Injected With Lipopolysaccharide to Vascular Proteoglycans Arterioscler. Thromb. Vasc. Biol. 2011

  17. Chow IT, James EA, Tan V, Moustakas AK, Papadopoulos GK, and Kwok WW. DRB1*12:01 presents a unique subset of epitopes by preferring aromatics in pocket 9 Mol. Immunol. 2011

  18. Delong JH, Simpson KH, Wambre E, James EA, Robinson D, and Kwok WW. Ara h 1-reactive T cells in individuals with peanut allergy J. Allergy Clin. Immunol. 127:1211-1218, 2011

  19. Eaton JE, Silveira MG, Pardi DS, Sinakos E, Kowdley KV, Luketic VA, Harrison ME, McCashland T, Befeler AS, Harnois D, Jorgensen R, Petz J, and Lindor KD. High-dose ursodeoxycholic acid is associated with the development of colorectal neoplasia in patients with ulcerative colitis and primary sclerosing cholangitis Am. J. Gastroenterol. 106:1638-1645, 2011

  20. Evanko SP, Potter-Perigo S, Bollyky PL, Nepom GT, and Wight TN. Hyaluronan and versican in the control of human T-lymphocyte adhesion and migration Matrix Biol. 2011

  21. Fu Y, Nagy JA, Brown LF, Shih SC, Johnson PY, Chan CK, Dvorak HF, and Wight TN. Proteolytic Cleavage of Versican and Involvement of ADAMTS-1 in VEGF-A/VPF-Induced Pathological Angiogenesis J. Histochem. Cytochem. 59:463-473, 2011

  22. Gallagher MP, Goland RS, and Greenbaum CJ. Making progress: preserving beta cells in type 1 diabetes Ann. N. Y. Acad. Sci. 1243:119-134, 2011

  23. Ge X, James EA, Reijonen H, and Kwok WW. Differences in self-peptide binding between T1D-related susceptible and protective DR4 subtypes J. Autoimmun. 2011

  24. Glatigny S, Duhen R, Oukka M, and Bettelli E. Cutting Edge: Loss of alpha4 Integrin Expression Differentially Affects the Homing of Th1 and Th17 Cells J. Immunol. 2011

  25. Greenbaum CJ and Atkinson MA. Persistence is the twin sister of excellence: an important lesson for attempts to prevent and reverse type 1 diabetes Diabetes 60:693-694, 2011

  26. Greenbaum CJ, Buckingham B, Chase H, and Krischer J. Metabolic Tests to Determine Risk for Type 1 Diabetes in Clinical Trials. Diabetes Metab Res. Rev. 2011

  27. Greenbaum CJ, McCulloch-Olson M, Chiu HK, Palmer JP, and Brooks-Worrell B. Parenteral insulin suppresses T cell proliferation to islet antigens. Pediatr. Diabetes 12:150-155, 2011

  28. Gruessner RW, Pugliese A, Reijonen HK, Gruessner S, Jie T, Desai C, Sutherland DE, and Burke GW III. Development of diabetes mellitus in living pancreas donors and recipients Expert. Rev. Clin. Immunol. 7:543-551, 2011

  29. Guo Y, Audry M, Ciancanelli M, Alsina L, Azevedo J, Herman M, Anguiano E, Sancho-Shimizu V, Lorenzo L, Pauwels E, Philippe PB, Perez de Diego R, Cardon A, Vogt G, Picard C, Andrianirina ZZ, Rozenberg F, Lebon P, Plancoulaine S, Tardieu M, Valerie D, Jouanguy E, Chaussabel D, Geissmann F, Abel L, Casanova JL, and Zhang SY. Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity J. Exp. Med. 208:2083-2098, 2011

  30. Hambleton S, Salem S, Bustamante J, Bigley V, Boisson-Dupuis S, Azevedo J, Fortin A, Haniffa M, Ceron-Gutierrez L, Bacon CM, Menon G, Trouillet C, McDonald D, Carey P, Ginhoux F, Alsina L, Zumwalt TJ, Kong XF, Kumararatne D, Butler K, Hubeau M, Feinberg J, Al-Muhsen S, Cant A, Abel L, Chaussabel D, Doffinger R, Talesnik E, Grumach A, Duarte A, Abarca K, Moraes-Vasconcelos D, Burk D, Berghuis A, Geissmann F, Collin M, Casanova JL, and Gros P. IRF8 Mutations and Human Dendritic-Cell Immunodeficiency N. Engl. J. Med. 2011

  31. Harada M, Hirota T, Jodo AI, Hitomi Y, Sakashita M, Tsunoda T, Miyagawa T, Doi S, Kameda M, Fujita K, Miyatake A, Enomoto T, Noguchi E, Masuko H, Sakamoto T, Hizawa N, Suzuki Y, Yoshihara S, Adachi M, Ebisawa M, Saito H, Matsumoto K, Nakajima T, Mathias RA, Rafaels N, Barnes KC, Himes BE, Duan QL, Tantisira KG, Weiss ST, Nakamura Y, Ziegler SF, and Tamari M. Thymic stromal lymphopoietin gene promoter polymorphisms are associated with susceptibility to bronchial asthma Am. J. Respir. Cell Mol. Biol. 44:787-793, 2011

  32. Harten IA, Zahr RS, Lemire JM, Machan JT, Moses MA, Doiron RJ, Curatolo AS, Rothman FG, Wight TN, Toole BP, Gordon LB.  Age-dependent loss of MMP-3 in Hutchinson-Gilford Progeria Syndrome.  J Gerontol A Biol Sci Med Sci.  66:1201-7, 2011.  

  33. Harten IA, Zahr RS, Lemire JM, Machan JT, Moses MA, Doiron RJ, Curatolo AS, Rothman FG, Wight TN, Toole BP, and Gordon LB. Age-dependent loss of MMP-3 in Hutchinson-Gilford progeria syndrome J. Gerontol. A Biol. Sci. Med. Sci. 66:1201-1207, 2011

  34. Hernaez R, Yeung E, Clark JM, Kowdley KV, Brancati FL, and Kao WH. Hemochromatosis gene and nonalcoholic fatty liver disease: a systematic review and meta-analysis J. Hepatol. 2011

  35. Ho MT, Kelly EJ, Bodor M, Bui T, Kowdley KV, and Ho RJ. Novel cytochrome P450-2D6 promoter sequence variations in hepatitis C positive and negative subjects Ann. Hepatol. 10:327-332, 2011

  36. Imam MH, Sinakos E, Gossard AA, Kowdley KV, Luketic VA, Harrison M, McCashland T, Befeler AS, Harnois D, Jorgensen R, Petz J, Keach J, Decook AC, Enders F, and Lindor KD. High-dose ursodeoxycholic acid increases risk of adverse outcomes in patients with early stage primary sclerosing cholangitis Aliment. Pharmacol. Ther. 34:1185-1192, Immunol. 2011

  37. Irani S, Kowdley K, Kozarek R. Gastric varices: an updated review of management. J Clin Gastroenterol. 45(2):133-48, 2011

  38. Ito H and Hamerman JA. TREM-2, triggering receptor expressed on myeloid cell-2, negatively regulates TLR responses in dendritic cells Eur. J. Immunol. 2011

  39. James EA and Kwok WW. Autoreactive CD4(+) T cells in patients with atopic dermatitis J. Allergy Clin. Immunol. 128:100-101, 2011

  40. James EA, Devoti JA, Rosenthal DW, Hatam LJ, Steinberg BM, Abramson AL, Kwok WW, and Bonagura VR. Papillomavirus-Specific CD4+ T Cells Exhibit Reduced STAT-5 Signaling and Altered Cytokine Profiles in Patients with Recurrent Respiratory Papillomatosis J. Immunol. 2011

  41. James EA, Mallone R, Schloot NC, Gagnerault MC, Thorpe J, Fitzgerald-Miller L, Reichow J, Wagner R, Pham MN, Jospe N, Lou O, Gottlieb PA, Brooks-Worrell BM, Durinovic-Belló I. Immunology of Diabetes Society T-Cell Workshop: HLA class II tetramer-directed epitope validation initiative. Diabetes Metab Res Rev 2011; 27: Eupub. DOI: 10.1002/dmrr.1244

  42. James EA, van Haren SD, Ettinger RA, Fijnvandraat K, Liberman JA, Kwok WW, Voorberg J, and Pratt KP. T-cell responses in two unrelated hemophilia A inhibitor subjects include an epitope at the factor VIII R593C missense site J. Thromb. Haemost. 2011

  43. Kawamoto S, Flynn JP, Shi Q, Sakr SW, Luo J, Allen MD. Heme oxygenase-1 induction enhances cell survival and restores contractility to unvascularized three-dimensional adult cardiomyocyte grafts implanted in vivo. Tissue Eng Part A. 2011 Feb 3. [Epub ahead of print]

  44. Kean TJ, Duesler L, Young RG, Dadabayev A, Olenyik A, Penn M, Wagner J, Fink DJ, Caplan AI, and Dennis JE. Development of a peptide-targeted, myocardial ischemia-homing, mesenchymal stem cell J. Drug Target 2011

  45. Khadra A, Pietropaolo M, Nepom GT, and Sherman A. Investigating the role of T-cell avidity and killing efficacy in relation to type 1 diabetes prediction PLoS. One. 6:e14796

  46. Killebrew JR, Perdue N, Kwan A, Thornton AM, Shevach EM, and Campbell DJ. A Self-Reactive TCR Drives the Development of Foxp3+ Regulatory T Cells That Prevent Autoimmune Disease J. Immunol. 187:861-869, 2011

  47. Kistler KD, Brunt EM, Clark JM, Diel AM, Sallis JF, and Schwimmer JB, for the NASH CRN Research Group [Kowdley KV]: Physical activity recommendations, exercise intensity, and histological severity of nonalcoholic fatty liver disease.  Am J Gastroenterol 2011 Mar;106(3):460-8. Epub 2011 Jan 4.

  48. Kitajima M, Ito T, Tumes DJ, Endo Y, Onodera A, Hashimoto K, Motohashi S, Yamashita M, Nishimura T, Ziegler SF, and Nakayama T. Memory type 2 helper T cells induce long-lasting antitumor immunity by activating natural killer cells Cancer Res. 71:4790-4798, 2011

  49. Kitajima M, Lee HC, Nakayama T, and Ziegler SF. TSLP enhances the function of helper type2 cells Eur. J. Immunol. 2011

  50. Kornum BR, Kawashima M, Faraco J, Lin L, Rico TJ, Hesselson S, Axtell RC, Kuipers H, Weiner K, Hamacher A, Kassack MU, Han F, Knudsen S, Li J, Dong X, Winkelmann J, Plazzi G, Nevsimalova S, Hong SC, Honda Y, Honda M, Hogl B, Ton TG, Montplaisir J, Bourgin P, Kemlink D, Huang YS, Warby S, Einen M, Eshragh JL, Miyagawa T, Desautels A, Ruppert E, Hesla PE, Poli F, Pizza F, Frauscher B, Jeong JH, Lee SP, Strohl KP, Longstreth WT Jr, Kvale M, Dobrovolna M, Ohayon MM, Nepom GT, Wichmann HE, Rouleau GA, Gieger C, Levinson DF, Gejman PV, Meitinger T, Peppard P, Young T, Jennum P, Steinman L, Tokunaga K, Kwok PY, Risch N, Hallmayer J, and Mignot E. Common variants in P2RY11 are associated with narcolepsy Nat. Genet. 43:66-71, 2011

  51. Kotturi MF, Swann JA, Peters B, Arlehamn CL, Sidney J, Kolla RV, James EA, Akondy RS, Ahmed R, Kwok WW, Buchmeier MJ, and Sette A. Human CD8+ and CD4+ T Cell Memory to Lymphocytic Choriomeningitis Virus Infection J. Virol. 85:11770-11780, 2011

  52. Kowdley KV, Belt P, Wilson LA, Yeh MM, Neuschwander-Tetri BA, Chalasani N, Sanyal AJ, and Nelson JE. Elevated serum ferritin is an independent predictor of histologic severity and advanced fibrosis among patients with nonalcoholic fatty liver disease Hepatology 2011

  53. Kowdley KV, Wang CC, Welch S, Roberts H, and Brosgart CL. Prevalence of chronic hepatitis B among foreign-born persons living in the United States by country of origin Hepatology doi: 10.1002/hep.24804., Nov 22, 2011

  54. Kreutziger KL, Muskheli V, Johnson P, Braun K, Wight TN, and Murry CE. Developing Vasculature and Stroma in Engineered Human Myocardium Tissue Eng Part A 2011

  55. Lachin JM, McGee PL, Greenbaum CJ, Palmer J, Pescovitz MD, Gottlieb P, and Skyler J. Sample size requirements for studies of treatment effects on beta-cell function in newly diagnosed type 1 diabetes PLoS. One. 6:e26471-2011

  56. Lavine JE, Schwimmer JB, Van Natta ML, Molleston JP, Murray KF, Rosenthal P, Abrams SH, Scheimann AO, Sanyal AJ, Chalasani N, Tonascia J, Ünalp A, Clark JM, Brunt EM, Kleiner DE, Hoofnagle JH, Robuck PR; Nonalcoholic Steatohepatitis Clinical Research Network[Kowdley KV]. Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: the TONIC randomized controlled trial. JAMA. 305(16):1659-68. 2011

  57. Long SA, Cerosaletti K, Wan JY, Ho JC, Tatum M, Wei S, Shilling HG, and Buckner JH. An autoimmune-associated variant in PTPN2 reveals an impairment of IL-2R signaling in CD4(+) T cells Genes Immun. 12:116-125, 2011

  58. Long SA, Rieck M, Tatum M, Bollyky PL, Wu RP, Muller I, Ho JC, Shilling HG, and Buckner JH. Low-dose antigen promotes induction of FOXP3 in human CD4+ T cells J. Immunol. 187:3511-3520, 2011

  59. Long SA. and Buckner JH. CD4+FOXP3+ T regulatory cells in human autoimmunity: more than a numbers game J. Immunol. 187:2061-2066, 2011

  60. Longhi MS, Hussain MJ, Kwok WW, Mieli-Vergani G, Ma Y, and Vergani D. Autoantigen-specific regulatory T cells, a potential tool for immune-tolerance reconstitution in type-2 autoimmune hepatitis Hepatology 53:536-547, 2011

  61. Lord JD, Hackman RC, Gooley TA, Wood BL, Moklebust AC, Hockenbery DM, Steinbach G, Ziegler SF, and McDonald GB. Blood and gastric FOXP3+ T cells are not decreased in human gastric graft-versus-host disease Biol. Blood Marrow Transplant. 17:486-496, 2011

  62. Lord JD, Upton MP, and Hwang JH. Confocal endomicroscopic evaluation of colorectal squamous metaplasia and dysplasia in ulcerative colitis Gastrointest. Endosc. 73:1064-1066, 2011

  63. Maliken BD, Nelson JE, and Kowdley KV. The hepcidin circuits act: Balancing iron and inflammation Hepatology 53:1764-1766, 2011

  64. Mallone R, Mannering SI, Brooks-Worrell BM, Durinovic-Belló I, Cilio CM, Wong FS, and Schloot NC. Isolation and preservation of peripheral blood mononuclear cells for analysis of islet antigen-reactive T cell responses: position statement of the T-Cell Workshop Committee of the Immunology of Diabetes Society Clin. Exp. Immunol. 163:33-49, 2011

  65. Mallone R, Scotto M, Janicki CN, James EA, Fitzgerald-Miller L, Wagner R, Gottlieb P, Thorpe J, Jospe N, Durinovic-Bellò I, Boitard C, Lou O, Dayan CM, Wong FS. Immunology of Diabetes Society T-Cell Workshop: HLA Class I Tetramer-Directed Epitope Validation Initiative. Diabetes Metab Res Rev; 27: Epub, DOI: 10.1002/dmrr.1245, 2011

  66. Matsumoto S, Takita M, Chaussabel D, Noguchi H, Shimoda M, Sugimoto K, Itoh T, Chujo D, Sorelle J, Onaca N, Naziruddin B, and Levy MF. Improving Efficacy of Clinical Islet Transplantation with Iodixanol Based Islet Purification, Thymoglobulin Induction and Blockage of IL-1-beta and TNF-alpha Cell Transplant. 2011

  67. Mattapallil MJ, Silver PB, Mattapallil JJ, Horai R, Karabekian Z, McDowell JH, Chan CC, James EA, Kwok WW, Sen HN, Nussenblatt RB, David CS, and Caspi RR. Uveitis-associated epitopes of retinal antigens are pathogenic in the humanized mouse model of uveitis and identify autoaggressive T cells J. Immunol. 187:1977-1985, 2011

  68. McNab FW, Berry MP, Graham CM, Bloch SA, Oni T, Wilkinson KA, Wilkinson RJ, Kon OM, Banchereau J, Chaussabel D, and O'Garra A. Programmed Death Ligand 1 is over-expressed by neutrophils in the blood of patients with active Tuberculosis Eur. J. Immunol. 2011

  69. Menard L, Saadoun D, Isnardi I, Ng YS, Meyers G, Massad C, Price C, Abraham C, Motaghedi R, Buckner JH, Gregersen PK, and Meffre E. The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans J. Clin. Invest 2011

  70. Merrilees MJ, Beaumont BW, Braun KR, Thomas AC, Kang I, Hinek A, Passi A, and Wight TN. Neointima Formed by Arterial Smooth Muscle Cells Expressing Versican Variant V3 Is Resistant to Lipid and Macrophage Accumulation Arterioscler. Thromb. Vasc. Biol. 2011

  71. Nelson JE, Klintworth H, Kowdley KV. Iron Metabolism in Nonalcoholic Fatty Liver Disease. Curr Gastroenterol Rpts.

  72. Nelson JE, Wilson L, Brunt EM, Yeh MM, Kleiner DE, Unalp-Arida A, and Kowdley KV. Relationship between the pattern of hepatic iron deposition and histological severity in nonalcoholic fatty liver disease Hepatology 53:448-457, 2011

  73. Nepom GT, St Clair EW, and Turka LA. Challenges in the pursuit of immune tolerance Immunol. Rev. 241:49-62, 2011

  74. Orban T, Bundy B, Becker DJ, DiMeglio LA, Gitelman SE, Goland R, Gottlieb PA, Greenbaum CJ, Marks JB, Monzavi R, Moran A, Raskin P, Rodriguez H, Russell WE, Schatz D, Wherrett D, Wilson DM, Krischer JP, and Skyler JS. Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial. Lancet 378:412-419, 2011

  75. Palomares O, Ruckert B, Jartti T, Kucuksezer UC, Puhakka T, Gomez E, Fahrner HB, Speiser A, Jung A, Kwok WW, Kalogjera L, Akdis M, and Akdis CA. Induction and maintenance of allergen-specific FOXP3(+) Treg cells in human tonsils as potential first-line organs of oral tolerance J. Allergy Clin. Immunol. 2011

  76. Peng SL. Psoriatic Arthritis. Virginia Mason Med Ctr Bull 65: 32-35 (2011)

  77. Pescovitz MD, Torgerson TR, Ochs HD, Ocheltree E, McGee P, Krause-Steinrauf H, Lachin JM, Canniff J, Greenbaum CJ, Herold KC, Skyler JS, and Weinberg A. Effect of rituximab on human in vivo antibody immune responses J. Allergy Clin. 

  78. Peters A, Pitcher LA, Sullivan JM, Mitsdoerffer M, Acton SE, Franz B, Wucherpfennig K, Turley S, Carroll MC, Sobel RA, Bettelli E, and Kuchroo VK. Th17 cells induce ectopic lymphoid follicles in central nervous system tissue inflammation Immunity. 35:986-996, 2011

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