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Scientific Papers

2012 BRI Publications

  1. Aarntzen EH, de Vries IJ, Lesterhuis WJ, Schuurhuis D, Jacobs JF, Bol K, Schreibelt G, Mus R, De Wilt JH, Haanen JB, Schadendorf D, Croockewit S, Blokx WA, van Rossum MM, Kwok WW, Adema GJ, Punt CJ, Figdor CG. Targeting CD4+ T helper cells improves the induction of anti-tumor responses in dendritic cell-based vaccination. Cancer Res. 2012 Oct 18. PMID: 23087058

  2. Arlehamn CS, Sidney J, Henderson R, Greenbaum JA, James EA, Moutaftsi M, Coler R, McKinney DM, Park D, Taplitz R, Kwok WW, Grey H, Peters B, Sette A. Dissecting Mechanisms of Immunodominance to the Common Tuberculosis Antigens ESAT-6, CFP10, Rv2031c (hspX), Rv2654c (TB7.7), and Rv1038c (EsxJ). J Immunol. 2012 May 15;188(10):5020-31. PMID: 22504645

  3. Arnaud L, Devilliers H, Peng SL, Mathian A, Costedoat-Chalumeau N, Buckner JH, Dagna L, Michet C, Sharma A, Cervera R, Haroche J, Papo T, D'Cruz D, Arlet P, Zwerina J, Belot A, Suzuki N, Harle JR, Moots R, Jayne D, Hachulla E, Marie I, Tanaka T, Lebovics R, Scott D, Kucharz EJ, Birchall M, Kong KO, Gorochov G, Amoura Z. The Relapsing Polychondritis Disease Activity Index: Development of a disease activity score for relapsing polychondritis. Autoimmun Rev. 2012 Jul 5. PMID: 22771427

  4. Ayars AG, Altman LC, Potter-Perigo S, Radford K, Wight TN, Nair P. Sputum Hyaluronan and Versican in Severe Eosinophilic Asthma. Int Arch Allergy Immunol. 2012 Dec 14;161(1):65-73. PMID: 23257685

  5. Banchereau R, Jordan-Villegas A, Ardura M, Mejias A, Baldwin N, Xu H, Saye E, Rossello-Urgell J, Nguyen P, Blankenship D, Creech CB, Pascual V, Banchereau J, Chaussabel D, Ramilo O. Host immune transcriptional profiles reflect the variability in clinical disease manifestations in patients with Staphylococcus aureus infections. PLoS One. 2012;7(4):e34390. PMID: 22496797

  6. Barton FB, Rickels MR, Alejandro R, Hering BJ, Wease S, Naziruddin B, Oberholzer J, Odorico JS, Garfinkel MR, Levy M, Pattou F, Berney T, Secchi A, Messinger S, Senior PA, Maffi P, Posselt A, Stock PG, Kaufman DB, Luo X, Kandeel F, Cagliero E, Turgeon NA, Witkowski P, Naji A, O'Connell PJ, Greenbaum CJ, Kudva YC, Brayman KL, Aull MJ, Larsen C, Kay TW, Fernandez LA, Vantyghem MC, Bellin M, Shapiro AM. Improvement in outcomes of clinical islet transplantation: 1999-2010. Diabetes Care. 2012 Jul;35(7):1436-45. PMID: 22723582

  7. Bell LN, Wang J, Muralidharan S, Chalasani S, Fullenkamp AM, Wilson LA, Sanyal AJ, Kowdley KV, Neuschwander-Tetri BA, Brunt EM, McCullough AJ, Bass NM, Diehl AM, Unalp-Arida A, Chalasani N; for the NASH CRN [Kowdley KV]. Relationship between adipose tissue insulin resistance and liver histology in nonalcoholic steatohepatitis: A pioglitazone versus vitamin E versus placebo for the treatment of nondiabetic patients with nonalcoholic steatohepatitis trial follow-up study. Hepatology. 2012 Apr 24. PMID: 22532269

  8. Bettini ML, Pan F, Bettini M, Finkelstein D, Rehg JE, Floess S, Bell BD, Ziegler SF, Huehn J, Pardoll DM, Vignali DA. Loss of Epigenetic Modification Driven by the Foxp3 Transcription Factor Leads to Regulatory T Cell Insufficiency. Immunity. 2012 May 25;36(5):717-30. PMID: 22579476

  9. Bloom CI, Graham CM, Berry MP, Wilkinson KA, Oni T, Rozakeas F, Xu Z, Rossello-Urgell J, Chaussabel D, Banchereau J, Pascual V, Lipman M, Wilkinson RJ, O'Garra A. Detectable changes in the blood transcriptome are present after two weeks of antituberculosis therapy. PLoS One. 2012;7(10):e46191. PMID: 23056259

  10. Boisson B, Laplantine E, Prando C, Giliani S, Israelsson E, Xu Z, Abhyankar A, Israël L, Trevejo-Nunez G, Bogunovic D, Cepika AM, Macduff D, Chrabieh M, Hubeau M, Bajolle F, Debré M, Mazzolari E, Vairo D, Agou F, Virgin HW, Bossuyt X, Rambaud C, Facchetti F, Bonnet D, Quartier P, Fournet JC, Pascual V, Chaussabel D, Notarangelo LD, Puel A, Israël A, Casanova JL, Picard C. Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency. Nat Immunol. 2012 Oct 28. doi: 10.1038/ni.2457. PMID: 23104095

  11. Bollyky PL, Bogdani M, Bollyky JB, Hull RL, Wight TN. The Role of Hyaluronan and the Extracellular Matrix in Islet Inflammation and Immune Regulation. Curr Diab Rep. 2012 Oct;12(5):471-80. PMID: 22810951

  12. Bonvalet M, Moussu H, Wambre E, Ricarte C, Horiot S, Rimaniol AC, Kwok WW, Horak F, de Beaumont O, Baron-Bodo V, Moingeon P. Allergen-specific CD4(+) T cell responses in peripheral blood do not predict the early onset of clinical efficacy during grass pollen sublingual immunotherapy. Clin Exp Allergy. 2012 Dec;42(12):1745-55. doi: 10.1111/cea.12015. PMID: 23181790

  13. Braun KR, DeWispelaere AM, Bressler SL, Jordan BJ, Fukai N, Kenagy RD, Chen L, Clowes AW, Kinsella MG. Inhibition of PDGF-B induction and Cell Growth by Syndecan-1 involves the Ubiquitin and SUMO-1 Ligase, Topors. PLoS One. 2012;7(8):e43701. PMID: 22912899

  14. Chandok N, Kamath PS, Blei A, Bosch J, Carey W, Grace N, Kowdley K, Benner K, Groszmann RJ. Randomised clinical trial: the safety and efficacy of long-acting octreotide in patients with portal hypertension. Aliment Pharmacol Ther. 2012 Apr;35(8):904-12. PMID: 22380529

  15. Chang HH, Soderberg K, Skinner JA, Banchereau J, Chaussabel D, Haynes BF, Ramoni M, Letvin NL. Transcriptional network predicts viral set point during acute HIV-1 infection. J Am Med Inform Assoc. 2012 Jun 14. PMID: 22700869

  16. Chang MY, Chan CK, Braun KR, Green PS, O'Brien KD, Chait A, Day AJ, Wight TN. Monocyte to macrophage differentiation: Synthesis and secretion of a complex extracellular matrix. J Biol Chem. 2012 Apr 20;287(17):14122-35. PMID: 22351750

  17. Chau JP, Chung LC, Wong RY, Loo KM, Lo SH, So TT, Lau MS, Yeung TH, Leung BS, Tong ML, Li CY, Kwok WW, Thompson DR, Lee DT. An Evaluation of a Web-Based Diabetes Education Program Designed to Enhance Self-management Among Patients Living With Diabetes. Comput Inform Nurs. 2012 Dec;30(12):672-679. PMID: 22872044

  18. Cheng Y, Stuart A, Morris K, Taylor R, Siddle HV, Deakin JE, Jones M, Amemiya CT, Belov K. Antigen presenting genes and genomic copy number variations in the Tasmanian devil MHC. BMC Genomics. 2012 Mar 12;13:87. PMID: 22404855

  19. Chiu HK, Sanda S, Fechner PY, Pihoker C. Correlation of TSH with the risk of paediatric thyroid carcinoma. Clin Endocrinol (Oxf). 2012 Aug;77(2):316-22. PMID: 22404106

  20. Chow IT, James EA, Tan V, Moustakas AK, Papadopoulos GK, Kwok WW. DRB1*12:01 presents a unique subset of epitopes by preferring aromatics in pocket 9. Mol Immunol. 2012 Feb;50(1-2):26-34. PMID: 22196942

  21. Crawford DHG, Fletcher LM, Kowdley KV. Iron and Liver Disease. Iron Physiology and Pathophysiology in Humans. GJ Anderson, GD McLaren (Eds). New York: Springer Science+Media, LLC, pp. 441-454, 2012. ISBN: 978-1-60327-485-2

  22. Crow KD, Smith CD, Cheng JF, Wagner GP, Amemiya CT. An independent genome duplication inferred from Hox paralogs in the American paddlefish-a representative basal ray-finned fish and important comparative reference. Genome Biol Evol. 2012 Jul 31. PMID: 22851613

  23. Dabelea D, Mayer-Davis EJ, Andrews JS, Dolan LM, Pihoker C, Hamman RF, Greenbaum C, Marcovina S, Fujimoto W, Linder B, Imperatore G, D'Agostino R Jr. Clinical evolution of beta cell function in youth with diabetes: the SEARCH for Diabetes in Youth study. Diabetologia. 2012 Dec;55(12):3359-68. Epub 2012 Sep 20. PMID: 22990715

  24. Deakin JE, Bender HS, Pearse A-M, Rens W, O'Brien PCM, Ferguson-Smith MA, Cheng Y, Morris K, Taylor R, Stuart A, Belov K, Amemiya CT, Murchison EP, Papenfuss AT, Graves JM. Genomic Restructuring in the Tasmanian Devil Facial Tumour: Chromosome Painting and Gene Mapping Provide Clues to Evolution of a Transmissible Tumour. PLoS Genet. 2012 Feb;8(2):e1002483. PMID: 22359511

  25. Duhen T, Duhen R, Lanzavecchia A, Sallusto F, Campbell DJ. Functionally distinct subsets of human FOXP3+ Treg cells that phenotypically mirror effector Th cells. Blood. 2012 May 10;119(19):4430-40. PMID: 22438251

  26. Greenbaum CJ, Beam CA, Boulware D, Gitelman SE, Gottlieb PA, Herold KC, Lachin JM, McGee P, Palmer JP, Pescovitz MD, Krause-Steinrauf H, Skyler JS, Sosenko JM. Fall in C-Peptide During First 2 Years From Diagnosis: Evidence of at Least Two Distinct Phases From Composite Type 1 Diabetes TrialNet Data. Diabetes. 2012 Aug;61(8):2066-2073. PMID: 22688329

  27. Greenbaum CJ, Schatz DA, Haller MJ, Sanda S. Response to Comment on: Greenbaum et al. Through the Fog: Recent Clinical Trials to Preserve beta-Cell Function in Type 1 Diabetes. Diabetes 2012;61:1323-1330. Diabetes. 2012 Dec;61(12):e19. doi: 10.2337/db12-0914. PMID: 23172965

  28. Greenbaum CJ, Schatz DA, Haller MJ, Sanda S. Through the fog: recent clinical trials to preserve ß-cell function in type 1 diabetes. Diabetes. 2012 Jun;61(6):1323-30. PMID: 22618767

  29. Greenbaum CJ. Dead or alive? Diabetes Care. 2012 Mar;35(3):459-60. PMID: 22355015

  30. Greenbaum CJ. Perspective: Rethink the immune connection. Nature. 2012 May 17;485(7398):S9. PMID: 22616097

  31. Habib T, Funk A, Rieck M, Brahmandam A, Dai X, Panigrahi A, Prak E, Meyer-Bahlmburg A, Sanda S, Greenbaum CJ, Rawlings D, Buckner JH. Altered B cell homeostasis is associated with type I diabetes and carriers of the PTPN22 allelic variant. J Immunol. 2012 Jan 1;188(1):487-96. PMID: 22105996

  32. Han H, Headley MB, Xu W, Comeau MR, Zhou B, Ziegler SF. Thymic Stromal Lymphopoietin Amplifies the Differentiation of Alternatively Activated Macrophages. J Immunol. 2012 Dec 28. [Epub ahead of print] PMID: 23275605

  33. Han H, Xu W, Headley MB, Jessup HK, Lee KS, Omori M, Comeau MR, Marshak-Rothstein A, Ziegler SF. Thymic stromal lymphopoietin (TSLP)-mediated dermal inflammation aggravates experimental asthma. Mucosal Immunol. 2012 May;5(3):342-51. PMID: 22354320

  34. Han J, Dakhama A, Jia Y, Wang M, Zeng W, Takeda K, Shiraishi Y, Okamoto M, Ziegler SF, Gelfand EW. Responsiveness to respiratory syncytial virus in neonates is mediated through thymic stromal lymphopoietin and OX40 ligand. J Allergy Clin Immunol. 2012 Nov;130(5):1175-1186.e9. PMID: 23036746

  35. Hanson NA, Auyong DB. Systematic Ultrasound Identification of the Dorsal Scapular and Long Thoracic Nerves During Interscalene Block. Reg Anesth Pain Med. 2012 Oct 17. [Epub ahead of print]. PMID: 23080352

  36. Herman M, Ciancanelli M, Ou YH, Lorenzo L, Klaudel-Dreszler M, Pauwels E, Sancho-Shimizu V, Perez de Diego R, Abhyankar A, Israelsson E, Guo Y, Cardon A, Rozenberg F, Lebon P, Tardieu M, Heropolitanska-Pliszka E, Chaussabel D, White MA, Abel L, Zhang SY, Casanova JL. Heterozygous TBK1 mutations impair TLR3 immunity and underlie herpes simplex encephalitis of childhood. J Exp Med. 2012 Aug 27;209(9):1567-82. PMID: 22851595

  37. Hondowicz BD, Schwedhelm KV, Kas A, Tasch MA, Rawlings C, Ramchurren N, McIntosh M, D’Amico LA, Sanda S, Standifer NE, Shendure J, Stone BC. Discovery of T cell antigens by high-throughput screening of synthetic minigene libraries. PLoS One. 2012;7(1):e29949. PMID: 22253836

  38. Hughes-Austin JM, Deane KD, Derber LA, Kolfenbach JR, Zerbe GO, Sokolove J, Lahey LJ, Weisman MH, Buckner JH, Mikuls TR, O'Dell JR, Keating RM, Gregersen PK, Robinson WH, Holers VM, Norris JM. Multiple cytokines and chemokines are associated with rheumatoid arthritis-related autoimmunity in first-degree relatives without rheumatoid arthritis: Studies of the Aetiology of Rheumatoid Arthritis (SERA). Ann Rheum Dis. 2012 Aug 21. PMID: 22915618

  39. Hull RL, Johnson PY, Braun KR, Day AJ, Wight TN. Hyaluronan and Hyaluronan Binding Proteins Are Normal Components of Mouse Pancreatic Islets and Are Differentially Expressed by Islet Endocrine Cell Types. J Histochem Cytochem. 2012 Jul 21. PMID: 22821669

  40. Hull RL, Peters MJ, Perigo SP, Chan CK, Wight TN, Kinsella MG. Overall Sulfation of Heparan Sulfate from Pancreatic Islet ß-TC3 Cells Increases Maximal Fibril Formation but Does Not Determine Binding to the Amyloidogenic Peptide Islet Amyloid Polypeptide. J Biol Chem. 2012 Oct 26;287(44):37154-64. PMID: 22936797

  41. Ioannidis I, McNally B, Willette M, Peeples ME, Chaussabel D, Durbin JE, Ramilo O, Mejias A, Flano E. Plasticity and Virus Specificity of the Airway Epithelial Cell Immune Response during Respiratory Virus Infection. J Virol. 2012 May;86(10):5422-36. PMID: 22398282

  42. Iseki M, Omori-Miyake M, Xu W, Sun X, Takaki S, Rawlings DJ, Ziegler SF. Thymic stromal lymphopoietin (TSLP)-induced polyclonal B-cell activation and autoimmunity are mediated by CD4+ T cells and IL-4. Int Immunol. 2012 Mar;24(3):183-95. PMID: 22281511

  43. Ito H, Hamerman JA. TREM-2, triggering receptor expressed on myeloid cell-2, negatively regulates TLR responses in dendritic cells. Eur J Immunol. 2012 Jan;42(1):176-85. PMID: 21956652

  44. Jackson AM, Kanak MA, Grishman E, Chaussabel D, Levy MF, Naziruddin B. Gene expression changes in human islets exposed to type 1 diabetic serum. Islets. 2012 Jul 1;4(4). PMID: 22885994

  45. Jacobson IM, Kowdley KV, Kwo PY.  Anemia Management in the Era of Triple Combination Therapy for Chronic HCV. Gastroenterology & Hepatology Clinical Roundtable Monograph. 2012;8(9):3-5, S6. PMID: Pending

  46. Jhingran A, Mar KB, Kumasaka DK, Knoblaugh SE, Ngo LY, Segal BH, Iwakura Y, Lowell CA, Hamerman JA, Lin X, Hohl TM. Tracing conidial fate and measuring host cell antifungal activity using a reporter of microbial viability in the lung. Cell Rep. 2012 Dec 27;2(6):1762-73. doi: 10.1016/j.celrep.2012.10.026. Epub 2012 Nov 29. PMID: 23200858

  47. Jones FC, Grabherr MG, Chan YF, Russell P, Mauceli E, Johnson J, Swofford R, Pirun M, Zody MC, White S, Birney E, Searle S, Schmutz J, Grimwood J, Dickson MC, Myers RM, Miller CT, Summers BR, Knecht AK, Brady SD, Zhang H, Pollen AA, Howes T, Amemiya CT; Broad Institute Genome Sequencing Platform & Whole Genome Assembly Team, Baldwin J, Bloom T, Jaffe DB, Nicol R, Wilkinson J, Lander ES, Di Palma F, Lindblad-Toh K, Kingsley DM. The genomic basis of adaptive evolution in threespine sticklebacks. Nature. 2012 Apr 4;484(7392):55-61. PMID: 22481358

  48. Kanter JE, Kramer F, Barnhart S, Averill MM, Vivekanandan-Giri A, Vickery T, Li LO, Becker L, Yuan W, Chait A, Braun KR, Potter-Perigo S, Sanda S, Wight TN, Pennathur S, Serhan CN, Heinecke JW, Coleman RA, Bornfeldt KE. Diabetes promotes an inflammatory macrophage phenotype and atherosclerosis through acyl-CoA synthetase 1. Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):E715-24. PMID: 22308341

  49. Kean TJ, Duesler L, Young RG, Dadabayev A, Olenyik A, Penn M, Wagner J, Fink DJ, Caplan AI, Dennis JE. Development of a peptide-targeted, myocardial ischemia-homing, mesenchymal stem cell. J Drug Target. 2012 Jan;20(1):23-32. PMID: 22047107

  50. Koch MA, Thomas KR, Perdue NR, Smigiel KS, Srivastava S, Campbell DJ. T-bet(+) Treg Cells Undergo Abortive Th1 Cell Differentiation due to Impaired Expression of IL-12 Receptor ß2. Immunity. 2012 Sep 21;37(3):501-10. PMID: 22960221

  51. Kong XF, Vogt G, Itan Y, Macura-Biegun A, Szaflarska A, Kowalczyk D, Chapgier A, Abhyankar A, Furthner D, Djambas Khayat C, Okada S, Bryant VL, Bogunovic D, Kreins A, Moncada-Vélez M, Migaud M, Al-Ajaji S, Al-Muhsen S, Holland SM, Abel L, Picard C, Chaussabel D, Bustamante J, Casanova JL, Boisson-Dupuis S. Haploinsufficiency at the human IFNGR2 locus contributes to mycobacterial disease. Hum Mol Genet. 2012 Nov 30. [Epub ahead of print] PMID: 23161749

  52. Kowdley KV. Response to Paul et al. Hepatology. 2012 Sep 17. doi: 10.1002/hep.26073. PMID: 22987775

  53. Kwok WW, Tan V, Gillette L, Littell CT, Soltis MA, LaFond RB, Yang J, James EA, Delong JH. Frequency of epitope-specific naive CD4(+) T cells correlates with immunodominance in the human memory repertoire. J Immunol. 2012 Mar 15;188(6):2537-44. PMID: 22327072

  54. Lee HC, Headley MB, Loo YM, Berlin A, Gale M Jr, Debley JS, Lukacs NW, Ziegler SF. Thymic stromal lymphopoietin is induced by respiratory syncytial virus-infected airway epithelial cells and promotes a type 2 response to infection. J Allergy Clin Immunol. 2012 Nov;130(5):1187-1196.e5. PMID: 22981788

  55. Lee HC, Sung SS, Krueger PD, Jo YA, Rosen HR, Ziegler SF, Hahn YS. Hepatitis C virus promotes Th17 responses through TSLP production by infected hepatocytes. Hepatology. 2012 Nov 13. PMID: 23150092

  56. Lee M, Kowdley KV. Alcohol's Effect on Other Chronic Liver Diseases. Clin Liver Dis. 2012 Nov;16(4):827-37. PMID: 23101984

  57. Lee Z, Dennis J, Welter J, Caplan A. Imaging stem cell differentiation for cell-based tissue repair. Methods Enzymol. 2012;506:247-63. PMID: 22341228

  58. Li Y, Kowdley KV. Cellular microRNA and the tumorigenesis of hepatocellular carcinoma. Ann Hepatol. 2012 Mar-Apr;11(2):272-4. PMID: 22345348

  59. Li Y, Kowdley KV. Method for microRNA isolation from clinical serum samples. Anal Biochem. 2012 Dec 1;431(1):69-75. Epub 2012 Sep 11. PMID: 22982505

  60. Li Y, Kowdley KV. MicroRNAs in Common Human Diseases. Genomics Proteomics Bioinformatics. 2012 Oct;10(5):246-53. doi: 10.1016/j.gpb.2012.07.005. Epub 2012 Sep 29. PMID: 23200134

  61. Lin OS, Kozarek RA, Gluck M, Jiranek GC, Koch J, Kowdley KV, Irani S, Nguyen M, Dominitz JA. Preference for Colonoscopy Versus Computerized Tomographic Colonography: A Systematic Review and Meta-analysis of Observational Studies. J Gen Intern Med. 2012 Jun 15. PMID: 22700393

  62. Liu Y, Goldberg AJ, Dennis JE, Gronowicz GA, Kuhn LT. One-step derivation of mesenchymal stem cell (MSC)-like cells from human pluripotent stem cells on a fibrillar collagen coating. PLoS One. 2012;7(3):e33225. PMID: 22457746

  63. Long SA, Rieck M, Sanda S, Bollyky JB, Samuels PL, Goland R, Ahmann A, Rabinovitch A, Aggarwal S, Phippard D, Turka LA, Ehlers MR, Bianchine PJ, Boyle KD, Adah SA, Bluestone JA, Buckner JH, Greenbaum CJ. Rapamycin/IL-2 Combination Therapy in Patients with Type 1 Diabetes Augments Tregs yet Transiently Impairs β-Cell Function. Diabetes. 2012 Sep;61(9):2340-8. PMID: 22721971

  64. Lord JD, Valliant-Saunders K, Hahn H, Thirlby RC, Ziegler SF. Paradoxically Increased FOXP3+ T Cells in IBD Do Not Preferentially Express the Isoform of FOXP3 Lacking Exon 2. Dig Dis Sci. 2012 Jun 27. PMID: 22736020

  65. Maliken BD, Avrin WF, Nelson JE, Mooney J, Kumar S, Kowdley KV. Room-temperature susceptometry predicts biopsy-determined hepatic iron in patients with elevated serum ferritin. Ann Hepatol. 2012 Jan-Feb;11(1):77-84. PMID: 22166564

  66. Matthis J, Nepom GT. T cell autoreactivity in the transplant milieu. Am J Transplant. 2012 Jul;12(7):1674-81. PMID: 22642536

  67. Maxwell KL, Kowdley KV. Metals and the liver. Curr Opin Gastroenterol. 2012 May;28(3):217-22. PMID: 22395570

  68. McCabe ME, Siddique A, Kowdley KV. ACP Journal Club. Adding N-acetylcysteine to prednisolone reduced early mortality in severe alcoholic hepatitis. Ann Intern Med. 2012 May 15;156(10):JC5-5. PMID: 22586023

  69. Messner D, Murray K, Kowdley KV. Mechanisms of Hepatocyte Detoxification. Physiology of the Gastrointestinal Tract, Fifth Edition. LR Johnson, FK Ghishan, JD Kaunitz, JL Merchant, HM Said, JD Wood (Eds). Academic Press, pp. 1507-1528, 2012. ISBN: 978-0-12-382026-6

  70. Mikuls TR, Thiele GM, Deane KD, Payne JB, O'Dell JR, Yu F, Sayles H, Weisman MH, Gregersen PK, Buckner JH, Keating RM, Derber LA, Robinson WH, Michael, Holers V, Norris JM. Porphyromonas gingivalis and disease-related autoantibodies in individuals at increased risk for future rheumatoid arthritis. Arthritis Rheum. 2012 Jun 26. PMID: 22736291

  71. Mounts T, Ginley N, Schluchter M, Dennis JE. Optimization of the expansion and differentiation of rabbit chondrocytes in vitro. Cartilage. 2012, Apr. 3(2): 181-187.

  72. Naik S, Bouladoux N, Wilhelm C, Molloy MJ, Salcedo R, Kastenmuller W, Deming C, Quinones M, Koo L, Conlan S, Spencer S, Hall JA, Dzutsev A, Kong H, Campbell DJ, Trinchieri G, Segre JA, Belkaid Y. Compartmentalized Control of Skin Immunity by Resident Commensals. Science. 2012 Aug 31;337(6098):1115-9. PMID: 22837383

  73. Nakajima S, Igyarto BZ, Honda T, Egawa G, Otsuka A, Hara-Chikuma M, Watanabe N, Ziegler SF, Tomura M, Inaba K, Miyachi Y, Kaplan DH, Kabashima K. Langerhans cells are critical in epicutaneous sensitization with protein antigen via thymic stromal lymphopoietin receptor signaling. J Allergy Clin Immunol. 2012 Apr;129(4):1048-55.e6. PMID: 22385635

  74. Nelson JE, Brunt EM, Kowdley KV. Lower serum hepcidin and greater parenchymal iron in nonalcoholic fatty liver disease patients with C282Y HFE mutations. Hepatology. 2012 May 21. PMID: 22611049

  75. Nepom GT, Buckner JH. A functional framework for interpretation of genetic associations in T1D. Curr Opin Immunol. 2012 Jul 25. PMID: 22841349

  76. Nepom GT. MHC class II tetramers. J Immunol. 2012 Mar 15;188(6):2477-82. PMID: 22389204

  77. Ni M, MacFarlane AW, Toft M, Lowell CA, Campbell KS, Hamerman JA. B-cell adaptor for PI3K (BCAP) negatively regulates Toll-like receptor signaling through activation of PI3K. Proc Natl Acad Sci U S A. 2012 Jan 3;109(1):267-72. PMID: 22187458

  78. Nishiura H, Kido M, Aoki N, Iwamoto S, Maruoka R, Ikeda A, Chiba T, Ziegler SF, Watanabe N. Increased susceptibility to autoimmune gastritis in thymic stromal lymphopoietin receptor-deficient mice. J Immunol. 2012 Jan 1;188(1):190-7. PMID: 22124119

  79. Oling V, Reijonen H, Simell O, Knip M, Ilonen J. Autoantigen-specific memory CD4(+) T cells are prevalent early in progression to Type 1 diabetes. Cell Immunol. 2012;273(2):133-9. PMID: 22270037

  80. Omori-Miyake M, Ziegler SF. Mouse Models of Allergic Diseases: TSLP and Its Functional Roles. Allergol Int. 2012 Mar;61(1):27-34. PMID: 22270069

  81. Palomares O, Ruckert B, Jartti T, Kucuksezer UC, Puhakka T, Gomez E, Fahrner HB, Speiser A, Jung A, Kwok WW, Kalogjera L, Akdis M, Akdis CA. Induction and maintenance of allergen-specific FOXP3+ Treg cells in human tonsils as potential first-line organs of oral tolerance. J Allergy Clin Immunol. 2012 Feb;129(2):510-20, 520.e1-9. PMID: 22051696

  82. Pan CQ, Tong M, Kowdley KV, Hu KQ, Chang TT, Lai CL, Yoon SK, Lee SS, Cohen D, Tang H, Tsai N. High Rates of Viral Suppression following Long-Term Entecavir Treatment of Asian Patients with HBeAg-Positive Chronic Hepatitis B. Clin Gastroenterol Hepatol. 2012 Sep;10(9):1047-1050.e1. PMID: 22475742

  83. Peng SL. Experimental use of mouse models of systemic lupus erythematosus. Methods Mol Biol. 2012;900:135-68. PMID: 22933068

  84. Plumb AW, Patton DT, Seo JH, Loveday EK, Jean F, Ziegler SF, Abraham N. Interleukin-7, but not thymic stromal lymphopoietin, plays a key role in the T cell response to influenza a virus. PLoS One. 2012;7(11):e50199. doi: 10.1371/journal.pone.0050199. Epub 2012 Nov 26. PMID: 23189186

  85. Poordad F, Bronowicki JP, Gordon SC, Zeuzem S, Jacobson IM, Sulkowski MS, Poynard T, Morgan TR, Molony C, Pedicone LD, Sings HL, Burroughs MH, Sniukiene V, Boparai N, Goteti VS, Brass CA, Albrecht JK, Bacon BR; SPRINT-2 and RESPOND-2 Investigators [Kowdley KV]. Factors that predict response of patients with hepatitis C virus infection to boceprevir. Gastroenterology. 2012 Sep;143(3):608-18.e1-5.

  86. Rabinowitz KM, Wang Y, Chen E, Hovhannisyan Z, Chiang D, Berin MC, Dahan S, Chaussabel D, Ma'ayan A, Mayer L. Transforming Growth Factor-b Signaling Controls Activities of Human Intestinal CD8+ T Suppressor Cells. Gastroenterology. 2012 Dec 8. doi:pii: S0016-5085(12)01744-1. 10.1053/j.gastro.2012.12.001. [Epub ahead of print] PMID: 23232296

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