Translational Research Program

Investigators:

Jane Buckner, MD, Associate Member, Program Director
Kris Kowdley, MD
S. Alice Long, PhD, Research Assistant Member
Brad Stone, PhD, Research Assistant Member
Karen Cerosaletti, PhD, Staff Scientist

Clinician Investigators at Virginia Mason Medical Center:

Mariko Kita, MD - Multiple Sclerosis
Anthony Gerbino, MD- Pulmonary Diseases
James Lord, MD, PhD - Inflammatory Bowel and Gastrointestinal Diseases
Kris Kowdley, MD – Hepatology
David Robinson, MD – Allergy Immunology

Laboratories:

Buckner Laboratory
Stone Laboratory

Core Facilities:

Array Core Laboratory
Clinical Core Laboratory
Sequencing and Genotyping Core Laboratory

The research emphasis of the BRI Translational Research Program is the area of immune mediated diseases. This includes the study of autoimmune and allergic diseases. The diseases that are being actively studied at this time include:

Type 1 Diabetes

Rheumatic Diseases with an emphasis on those diseases listed below:

• Relapsing polychondritis
• Rheumatoid Arthritis Link to Studies of the Etiology of Rheumatoid Arthritis (SERA)
• Scleroderma
• Systemic Lupus Erythematosus

Pulmonary Disease

• Asthma
• Scleroderma
• Idiopathic Pulmonary Fibrosis
• Sarcoidosis

Gastrointestinal Disease

• Ulcerative Colitis
• Crohn's Disease
• Hepatology

Neurologic Disease

• Multiple Sclerosis
• ALS or Lou Gehrig's Disease

Allergy

The Translational Research Program includes a group of Clinical Coordinators who interface with research participants, a Clinical Core Laboratory which handles and track all samples obtained from individuals, then transfers samples to the research laboratories.

Translational Research Program Group

Jane Buckner, MD
Christine Chan
Ami Charmley
Thien-Son Nguyen
Mark Bramlett
Rachel Rogers
Kate DeGraaff
Bert Park
Katherine Nickel
Amber Matheny
Jennifer Heaton
Kevin Criste