Genomics Platform

The Genomics Core provides resources to BRI and external investigators for gene expression analysis, from sample processing through data generation, as well as basic bioinformatics analysis, provided by our Bioinformatics Core Team.  Currently available technologies include whole genome microarrays and RNA-sequencing. 

The Core laboratory uses an Illumina HiScanSQ platform for gene expression profiling.  The HiScanSQ is a dual function instrument, combining a microarray scanner with a sequencing module.  The HiScan Reader, a high performance array scanner with sub-micron resolution, can image bead arrays, as well as sequencing flow cells.  The platform also includes the SQ module, an add-on fluidics device that delivers Illumina’s sequencing-by-synthesis reagents, and the cBot clonal amplification system that grows the DNA clusters.  Ancillary equipment for sample processing includes a Qiagen QIAgility (a fluid handling robot), an Agilent Bioanalyzer (to measure RNA/DNA integrity and size) and a Tecan NanoQuant (for high throughput sample quantitation).  Additionally, there is an Applied Biosystems StepOne Plus Real-Time qPCR instrument.

Availability: Services are available to BRI and VMMC investigators as well as outside investigators.

Manager: Vivian Gersuk, PhD

Contact:  For more information, please contact VGersuk@benaroyaresearch.org