Genome Resource Center
The Genome Resource Center (GRC) provides expertise in BAC (bacterial artificial chromosomes) library construction. Robotic equipment produces these colonies, which are genomic "libraries" that contain all of the DNA for a particular species-arrayed in a manner that allows specific fragments to be studied.
The GRC also provides expertise in infrastructure for arraying and spotting of any plasmid-based library (cDNAs, shotgun subclones, fosmids, BACs). The GRC contains robotic workstations for arraying of bacterial colonies into 384-well microtiter dishes and for gridding (spotting) of clones onto high-density nylon membranes (macroarrays) for hybridization screening.
Manager:
Availability:
There are usually no restrictions. An MTA or Collaborative Research Agreement is drafted that suits both parties involved. If it is a fee-for-service project, the resources so generated are the intellectual property of the requesting party. The GRC accepts collaborative and fee-for-service projects on a case-by-case basis.
Contact:
Chris Amemiya (camemiya@benaroyaresearch.org).