Research Assistant Member
Position #: 09-16
Position: Research Assistant Member,
Cardiac/Skeletal Muscle Bioengineering, Biology, & Regenerative Medicine
Department: Hope Heart Program, Allen Lab
Status: Full time
Responsibilities and Qualifications: The candidate is expected to be a scientist well-versed in the cellular biology of myocyte recovery from ischemic injury but who can creatively apply this knowledge in bioengineering and tissue repair strategies. Research in this laboratory spans the gamut from basic to translational research. This offering is an opportunity to conduct investigations under a recently awarded grant utilizing autologous cardiomyocytes in cardiac infarct repair, investigating preconditioning mechanisms responsible for adult myocyte recovery and plasticity. Other ongoing projects include construction of three-dimensional skeletal muscle for muscle repair; and embryonic-derived stem cell delivery for heart repair. Collaborating laboratories within the tissue engineering group at BRI focus on cardiovascular extracellular matrix, scaffold engineering, and immunology, providing many opportunities for cross-disciplinary research. Outside collaborators include University of Washington investigators in bioengineering and stem cell biology.
The candidate should be proficient in cellular and molecular biology; in assessment of myocyte function and heart function; in assessment of cell viability and angiogenesis in three-dimensional tissues; and be familiar with small animal models of myocardial infarction and hindlimb ischemia; viral vector construction and delivery; and have a good understanding of clinical heart failure. Qualifications include an M.D./Ph.D., M.D., or Ph.D. and sufficient postdoctoral research experience and/or faculty level experience to ensure the individual is capable of independent research and mentoring of staff and students. Excellent communication and language skills are required with demonstrated success in grantsmanship and an excellent publication record. Knowledge base should focus on basic myocyte biology as it relates to ischemia/reperfusion injury in cardiac and skeletal myocytes, pre/postconditioning, stem cell biology as it relates to the heart and skeletal muscle, ideally including research on induced pluripotency in adult cells, autophagy, extracellular matrix interactions, and/or cell senescence. We are looking for the unusual scientist with skills that cross over from basic science to translational research.
To be considered for this position the candidate must be eligible to work in the United States.
How to apply
Qualified candidates should email a resume and cover letter to jobs@benaroyaresearch.org and include the job number in the subject line.
BRI encourages and welcomes diversity. We are an equal opportunity and affirmative action employer. Applicants are considered for employment without regard to race, creed, color, religion, national origin, sex, age, disability, marital status, sexual orientation, status as a veteran, or any other basis prohibited by local, state, or federal laws. Applicants are encouraged to complete the voluntary applicant referral and affirmative action form.