Regimen 1: Chemotherapy with CT-2103 for a maximum of 12 total treatments. Regimen 2: Chemotehrapy with Paclitaxel for a maximum of 12 total treatments. Regimen 3: No anti-cancer treatment until evidence of disease progression.

Eligibiilty: ~Histological daignosis fo primary peritoneal carcinoma or epithelial ovarain carcinoma, Stage II or IV. ~Has completed treatmetn with the past 12 weeks with at least 5 cylces and no more than 8 cycles of platinum and paclitaxel or codetaxel-based combination chemotherapy and have no symptoms suggestive or persistant cancer. N~Normal CT scan of the abdomen/pelvis and normal CA-125 following treatment Ineligibility: ~Patients with current diagnosis of epithelial ovarian tumor of low malignant potential are not eligible. ~patietns who have recieved prior radiotherapy to any portion of the abdominal cavity or pelvis. ~Patients with synchronous primary endometrial cancer, or a past history of primary endometrial cancer. ~No other malignancies within the last 5 years

"A Ramdomized Phase III Trial of Maintenance Chemotherapy Comparing 12 Monthly Cycles of Single Agent Paclitaxel or CT-2103 Versus No Treatment Until Documented Relapse in Womne with Advanced Ovarian or Primary Peritoneal Cancer Who Achieve a Complete Clinical Response to Primary Platinu/Taxabe Chemotherapy"